Levamisole

Generic Name
Levamisole
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H12N2S
CAS Number
14769-73-4
Unique Ingredient Identifier
2880D3468G
Background

Levamisole is an antihelminthic drug that was commonly used for the treatment of parasitic, viral, and bacterial infections. It was manufactured by Janssen and first used in 1969 as an agent to treat worm infestations Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer. Prior to this, levamisole was used as an antirheumatic ...

Indication

For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.

Associated Conditions
Adenocarcinoma of Colon, Ancylostoma duodenale infection, Ascaris lumbricoides infection, Colorectal Carcinoma (CRC), Enterobius vermicularis infection, Necatoriasis due to necator americanus, Strongyloides Stercoralis Infection, Trichuris Infection
Associated Therapies
-

The Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule for Primary Nephrotic Syndrome in Children

First Posted Date
2023-03-16
Last Posted Date
2024-06-21
Lead Sponsor
Jianhua Zhou
Target Recruit Count
402
Registration Number
NCT05772871
Locations
🇨🇳

Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

🇨🇳

Anhui Children's Hospital, Hefei, Anhui, China

🇨🇳

Children's Hospital of Chongqing Medical University, Chongqing, Chongqing, China

and more 23 locations

Levamisole and Isoprinosine in Immune-prophylaxis of Egyptian Healthcare Workers Facing COVID-19

First Posted Date
2020-04-24
Last Posted Date
2020-05-05
Lead Sponsor
Ain Shams University
Target Recruit Count
100
Registration Number
NCT04360122
Locations
🇪🇬

Faculty of Medicine Ain Shams University Research Institute- Clinical Research Center, Cairo, Non-US, Egypt

Novel Treatment of Advanced Hepatocellular Carcinoma

First Posted Date
2019-05-15
Last Posted Date
2019-05-15
Lead Sponsor
The First Affiliated Hospital of Zhengzhou University
Target Recruit Count
300
Registration Number
NCT03950518
Locations
🇨🇳

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Efficacy and Safety of Levamisole Combined With Standard Prednisolone in Warm Antibody Autoimmune Hemolytic Anemia.

First Posted Date
2012-04-17
Last Posted Date
2012-04-19
Lead Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Target Recruit Count
100
Registration Number
NCT01579110
Locations
🇨🇳

Blood Diseases Hospital Chinese Academy of Medical Sciences, TianJin, Tianjin, China

Comparison of Efficacy of Azithromycin and Levamisole Versus of Azithromycin in in the Treatment of Acne

Phase 2
Completed
Conditions
Interventions
First Posted Date
2011-05-05
Last Posted Date
2011-05-05
Lead Sponsor
Ahvaz Jundishapur University of Medical Sciences
Target Recruit Count
169
Registration Number
NCT01348321
Locations
🇮🇷

Azadegan Street,Imam Hospital,Department of Dermatology, Ahvaz, Khoozestan, Iran, Islamic Republic of

Effect of Levamisole Supplementation on Tetanus Vaccination Response Rates in Hemodialysis Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-06-26
Last Posted Date
2013-07-26
Lead Sponsor
Shiraz University of Medical Sciences
Target Recruit Count
40
Registration Number
NCT00705692
Locations
🇮🇷

Faghihi Hospital Hemodialysis Center, Shiraz University of Medical Sciences, Shiraz, Fars, Iran, Islamic Republic of

Efficacy Albendazole and Levamisole Against STH on Unguja

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-04-17
Last Posted Date
2008-04-17
Lead Sponsor
Natural History Museum, United Kingdom
Target Recruit Count
20
Registration Number
NCT00659997
Locations
🇹🇿

Helminth Control Laboratory Unguja, Stone Town, Tanzania

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