MedPath

Orforglipron

Generic Name
Orforglipron

A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-07-21
Last Posted Date
2022-11-25
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
26
Registration Number
NCT05469126
Locations
🇸🇬

Lilly Centre for Clinical Pharmacology, Singapore, Singapore

A Study of Two Different Formulations of LY3502970 in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-04-22
Last Posted Date
2022-09-21
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
39
Registration Number
NCT05341089
Locations
🇸🇬

Lilly Centre for Clinical Pharmacology, Singapore, Singapore

A Study of LY3502970 in Healthy Overweight and Obese Participants

Phase 1
Completed
Conditions
Healthy
Obese
Interventions
First Posted Date
2022-04-06
Last Posted Date
2022-10-18
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
72
Registration Number
NCT05313802
Locations
🇺🇸

ICON Early Phase Services, San Antonio, Texas, United States

🇺🇸

Qps-Mra, Llc, Miami, Florida, United States

🇺🇸

ICON Early Phase Services Lenexa Center, Lenexa, Kansas, United States

A Multiple-Dose Study of LY3502970 in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2021-11-08
Last Posted Date
2022-06-23
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
33
Registration Number
NCT05110794
Locations
🇸🇬

Lilly Centre for Clinical Pharmacology, Singapore, Singapore

A Study of LY3502970 in Japanese Participants With Type 2 Diabetes Mellitus

Phase 1
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
Drug: Placebo
First Posted Date
2021-10-21
Last Posted Date
2022-11-28
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
62
Registration Number
NCT05086445
Locations
🇯🇵

Medical Corporation Heishinkai OPHAC Hospital, Osaka-shi, Osaka, Japan

🇯🇵

Clinical Research Hospital Tokyo, Shinjuku-ku, Tokyo, Japan

🇯🇵

P-One Clinic, Hachioji, Tokyo, Japan

and more 2 locations

A Multiple Dose Study of LY3502970 in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2021-09-21
Last Posted Date
2022-04-26
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
26
Registration Number
NCT05051566
Locations
🇬🇧

Quotient Clinical Ltd, Nottingham, United Kingdom

A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities

Phase 2
Completed
Conditions
Obesity
Overweight and Obesity
Interventions
Drug: Placebo
First Posted Date
2021-09-21
Last Posted Date
2023-09-13
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
272
Registration Number
NCT05051579
Locations
🇭🇺

DRC Gyógyszervizsgáló Központ, Balatonfüred, Veszprém, Hungary

🇺🇸

Anaheim Clinical Trials, LLC, Anaheim, California, United States

🇺🇸

Valley Clinical Trials, Inc., Northridge, California, United States

and more 32 locations

A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus

Phase 2
Completed
Conditions
Type 2 Diabetes
Interventions
First Posted Date
2021-09-17
Last Posted Date
2023-10-17
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
383
Registration Number
NCT05048719
Locations
🇸🇰

MEDI-DIA s.r.o., Sabinov, Prešovský Kraj, Slovakia

🇸🇰

Funkystuff, Nove Zamky, Slovakia

🇺🇸

Cotton O'Neil Clinical Research Center, Topeka, Kansas, United States

and more 41 locations

A Study of LY3502970 in Healthy Male Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: [¹⁴C]-LY3502970
First Posted Date
2020-12-23
Last Posted Date
2021-07-19
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
6
Registration Number
NCT04680767
Locations
🇬🇧

Covance Clinical Research, Leeds, United Kingdom

A Study of LY3502970 in Participants With Type 2 Diabetes

Phase 1
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
Drug: Placebo
First Posted Date
2020-06-11
Last Posted Date
2021-07-27
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
68
Registration Number
NCT04426474
Locations
🇩🇪

Profil Institut für Stoffwechselforschung, Neuss, Nordrhein-Westfalen, Germany

🇺🇸

Endeavor Clinical Trials, San Antonio, Texas, United States

🇺🇸

Hassman Research Institute, Marlton, New Jersey, United States

and more 3 locations
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