Interferon beta-1a
- Generic Name
- Interferon beta-1a
- Brand Names
- Avonex, Rebif
- Drug Type
- Biotech
- CAS Number
- 145258-61-3
- Unique Ingredient Identifier
- XRO4566Q4R
- Background
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
- Indication
For treatment of relapsing/remitting multiple sclerosis, also for condyloma acuminatum
- Associated Conditions
- Relapsing Multiple Sclerosis (RMS)
Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.
Phase 4
Withdrawn
- Conditions
- Demyelinating DisordersMultiple SclerosisOptic NeuritisMyelitisNeuritis
- First Posted Date
- 2002-05-17
- Last Posted Date
- 2018-04-12
- Lead Sponsor
- MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute
- Registration Number
- NCT00037115
- Locations
- 🇺🇸
MidAmerica Neuroscience Institute, Kansas City, Missouri, United States
Combination Therapy With Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis
Phase 4
Completed
- Conditions
- Multiple Sclerosis
- First Posted Date
- 2002-05-17
- Last Posted Date
- 2018-04-12
- Lead Sponsor
- MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute
- Target Recruit Count
- 16
- Registration Number
- NCT00037102
Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients With HTLV-1-Associated Myelopathy (HAM)
Phase 2
Completed
- Conditions
- Spinal Cord DiseaseTropical Spastic ParaparesisHTLV-I Infection
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 12
- Registration Number
- NCT00001785
- Locations
- 🇺🇸
National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.
© Copyright 2025. All Rights Reserved by MedPath