Potassium chloride

Generic Name: Potassium chloride

Brand Names: Bi-peglyte, Bss, Bss Ophthalmic Solution, Cardioplegic, Citrasate, Colyte, Dextrose and Electrolyte No. 75, Diphen, Eye Stream, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Glycerolyte 57, Golytely, H.E.L.P.bicel, Hemosate Ultra, Ionosol-MB, Isolyte P, Isolyte S, Isolyte S pH 7.4, Isoplate, K 45, K-tab, Klor-con, Lactated Ringers, Moviprep, Naturalyte, Normosol-R, Nulytely, Nxstage Pureflow, Olimel, Peglyte, Periolimel, Phoxillum, Physiolyte, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Plegisol, Plenvu, Pokonza, Prismasol, Procalamine 3, Ringers, Selectbag One, Suflave, Tis-U-sol

Drug Type: Small Molecule

Chemical Formula: ClK

CAS Number: 7447-40-7

Unique Ingredient Identifier: 660YQ98I10

Background: A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and those products formulated for preparation of solution prior to ingestion.

Indication: For use as an electrolyte replenisher and in the treatment of hypokalemia.

Associated Conditions: Dehydration, Dry Mouth, Hypokalemia, Hypotonic Dehydration, Hypovolaemia, Isotonic Dehydration, Markedly Reduced Food Intake, Metabolic Acidosis, Hypodermoclysis, Mild Metabolic acidosis, Mild, moderate Metabolic Acidosis, Ocular edema

Associated Therapies: Acid- Base Balance, Bowel preparation therapy, Electrolyte replacement, Fluid replacement therapy, Haemofiltration, Hemodialysis Treatment, Parenteral Nutrition, Parenteral rehydration therapy, Plasma Volume Replacement, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Clinical Trials

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

Phase 3

Recruiting

Conditions: Shock
Septic

Interventions: Drug: Normal Saline
Drug: Lactated Ringer
Drug: Plasma-lyte

First Posted Date: 2019-09-25

Last Posted Date: 2024-07-26

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 8800

Registration Number: NCT04102371

Locations: 🇺🇸
UCSF Benioff Children's Hospital, San Francisco, California, United States
🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
🇺🇸
Primary Children's: University of Utah, Salt Lake City, Utah, United States

and more 21 locations

Balanced Crystalloids in Postpartum Hemorrhage

Conditions: Postpartum Hemorrhage

Interventions: Drug: Lactate Ringer
Drug: Plasma-lyte

First Posted Date: 2019-01-31

Last Posted Date: 2019-02-04

Lead Sponsor: Fundación Santa Fe de Bogota

Target Recruit Count: 40

Registration Number: NCT03824743

Locations: 🇨🇴
Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia

The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy

Phase 2

Completed

Conditions: Acute Kidney Injury
Contrast-induced Nephropathy
Acute Coronary Syndrome

Interventions: Drug: Potassium Nitrate
Drug: Potassium Chloride

First Posted Date: 2018-08-13

Last Posted Date: 2022-12-16

Lead Sponsor: Barts & The London NHS Trust

Target Recruit Count: 640

Registration Number: NCT03627130

Locations: 🇬🇧
Barts Heart Centre, London, United Kingdom

Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS)

Phase 2

Completed

Conditions: Aortic Valve Stenosis

Interventions: Drug: Potassium Nitrate
Drug: Potassium Chloride

First Posted Date: 2018-03-29

Last Posted Date: 2020-06-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 5

Registration Number: NCT03483051

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders

Phase 2

Active, not recruiting

Conditions: Gastrointestinal Disorder
Autism Spectrum Disorder

Interventions: Drug: Vancomycin
Drug: MoviPrep
Biological: Full Spectrum Microbiota

First Posted Date: 2018-01-24

Last Posted Date: 2023-01-09

Lead Sponsor: Arizona State University

Target Recruit Count: 55

Registration Number: NCT03408886

Locations: 🇺🇸
Arizona State University, Tempe, Arizona, United States

Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

Phase 4

Completed

Conditions: Colorectal Cancer

Interventions: Drug: Golytely
Drug: Miralax-Gatorade Prep

First Posted Date: 2017-10-02

Last Posted Date: 2024-10-01

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 2261

Registration Number: NCT03298945

Locations: 🇺🇸
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia, Pennsylvania, United States

Comparison of Clenpiq vs Golytely Bowel Preparation

Phase 4

Terminated

Conditions: Bowel Preparation Solutions

Interventions: Drug: Golytely
Drug: Clenpiq

First Posted Date: 2017-06-26

Last Posted Date: 2021-03-04

Lead Sponsor: The Cleveland Clinic

Target Recruit Count: 14

Registration Number: NCT03198221

Locations: 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States

Double Blinded Randomized Control Trial of Types of IVF in Children With DKA

Phase 4

Terminated

Conditions: Diabetic Ketoacidosis

Interventions: Drug: Normal saline
Drug: Lactated Ringers

First Posted Date: 2017-02-28

Last Posted Date: 2024-08-06

Lead Sponsor: State University of New York at Buffalo

Target Recruit Count: 53

Registration Number: NCT03066440

Locations: 🇺🇸
John R. Oishei Children's Hospital, Buffalo, New York, United States

Comparative Analysis Between Ringer's Lactate vs Plasma Lyte-A as Cardiopulmonary Bypass Prime

Phase 3

Conditions: Cardiopulmonary Bypass

Interventions: Drug: Ringer Lactate
Drug: Plasmalyte A

First Posted Date: 2017-02-03

Last Posted Date: 2017-02-03

Lead Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

Target Recruit Count: 60

Registration Number: NCT03043131

Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy

Not Applicable

Conditions: Chromosome Abnormality
Twin Pregnancy With Antenatal Problem

Interventions: Procedure: Fetal Selective Reduction Technology
Drug: Potassium Chloride

First Posted Date: 2016-12-05

Last Posted Date: 2016-12-05

Lead Sponsor: Shanghai First Maternity and Infant Hospital

Target Recruit Count: 1300

Registration Number: NCT02982356

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