Potassium nitrate
- Generic Name
- Potassium nitrate
- Brand Names
- Meijer, Prevident 5000 Sensitive, Styptstix
- Drug Type
- Small Molecule
- Chemical Formula
- KNO3
- CAS Number
- 7757-79-1
- Unique Ingredient Identifier
- RU45X2JN0Z
- Background
Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste, exerting an anti-sensitivity action. It provides increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets or contact .
In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. It is administered orally doses up to 30 g per animal per day .
- Indication
For the relief of tooth sensitivity, and is also used as a pesticide, insecticide, as a food additive, and a rodenticide .
- Associated Conditions
- Sensitivity, Tooth
Matching Perfusion and Metabolic Activity in HFpEF
- Conditions
- Heart Failure With Preserved Ejection Fraction
- Interventions
- Other: Potassium Chloride
- First Posted Date
- 2021-06-04
- Last Posted Date
- 2025-02-19
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 53
- Registration Number
- NCT04913805
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy
- Conditions
- Acute Kidney InjuryContrast-induced NephropathyAcute Coronary Syndrome
- Interventions
- First Posted Date
- 2018-08-13
- Last Posted Date
- 2022-12-16
- Lead Sponsor
- Barts & The London NHS Trust
- Target Recruit Count
- 640
- Registration Number
- NCT03627130
- Locations
- 🇬🇧
Barts Heart Centre, London, United Kingdom
Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS)
- Conditions
- Aortic Valve Stenosis
- Interventions
- First Posted Date
- 2018-03-29
- Last Posted Date
- 2020-06-17
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 5
- Registration Number
- NCT03483051
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Anti-inflammatory Steroids in the Prevention of Tooth Sensitivity
- Conditions
- Inflammation
- Interventions
- First Posted Date
- 2016-11-04
- Last Posted Date
- 2020-11-25
- Lead Sponsor
- Universidade Federal Fluminense
- Target Recruit Count
- 70
- Registration Number
- NCT02956070
Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion
- Conditions
- Dental ErosionAcid Wear
- Interventions
- First Posted Date
- 2012-08-06
- Last Posted Date
- 2015-01-26
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 56
- Registration Number
- NCT01657903
- Locations
- 🇺🇸
Indiana University School of Dentistry, Indianapolis, Indiana, United States
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
- Conditions
- Dental PainDentinal Hypersensitivity
- Interventions
- Drug: Placebo
- First Posted Date
- 2012-04-30
- Last Posted Date
- 2015-04-28
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 12
- Registration Number
- NCT01587950
- Locations
- 🇺🇸
University Park Research Center (UPRC), Fort Wayne, Indiana, United States
Drug Development Updates
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