Ferroheme
- Generic Name
- Ferroheme
- Drug Type
- Small Molecule
- Chemical Formula
- C34H32FeN4O4
- CAS Number
- 14875-96-8
- Unique Ingredient Identifier
- 42VZT0U6YR
Heme Arginate in Transplantation Study
Phase 3
Terminated
- Conditions
- Renal Transplant RejectionRenal Transplant Failure
- Interventions
- Drug: 0.9% Sodium-chloride
- First Posted Date
- 2018-08-24
- Last Posted Date
- 2021-06-23
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 47
- Registration Number
- NCT03646344
- Locations
- π¬π§
Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom
π¬π§NHS Lothian - Royal Infirmary of Edinburgh, Edinburgh, Lothian, United Kingdom
The Effects of Intravenous Heme Arginate on Heme Oxygenase-1 Expression (HO-1) and Oxidative Stress in the Human Heart
Phase 2
Completed
- Conditions
- Myocardial Ischemia
- Interventions
- First Posted Date
- 2014-12-11
- Last Posted Date
- 2021-02-15
- Lead Sponsor
- Martin Andreas, M.D.
- Target Recruit Count
- 31
- Registration Number
- NCT02314780
- Locations
- π¦πΉ
Medical University of Vienna, Vienna, Austria
Heme Arginate in Functional Magnetic Resonance Imaging (fMRI)
Phase 2
- Conditions
- Ischemia-reperfusion Injury
- Interventions
- Drug: Placebo administration
- First Posted Date
- 2011-10-28
- Last Posted Date
- 2011-10-28
- Lead Sponsor
- MWolzt
- Target Recruit Count
- 16
- Registration Number
- NCT01461512
- Locations
- π¦πΉ
Medical University of Vienna, Department of Clinical Pharmacology, Vienna, Austria
Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation
Phase 3
Completed
- Conditions
- Graft FailureIschemia-reperfusion Injury
- Interventions
- First Posted Date
- 2011-09-07
- Last Posted Date
- 2015-05-27
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 40
- Registration Number
- NCT01430156
- Locations
- π¬π§
Royal Infirmary of Edinburgh/ University of Edinburgh, Edinburgh, Lothian, United Kingdom
Heme Oxygenase (HO) Activity and Adenosine Induced Vasodilation
Phase 4
Terminated
- Conditions
- Atherosclerotic Cardiovascular Disease
- Interventions
- First Posted Date
- 2009-03-06
- Last Posted Date
- 2011-08-11
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 6
- Registration Number
- NCT00856817
- Locations
- π³π±
Radboud University Nijmegen Medical Centre, Nijmegen, Gelderland, Netherlands
Heme Iron Polypeptide for Iron Deficiency Anemia in Chronic Renal Failure
Phase 2
Completed
- Conditions
- AnemiaRenal Failure
- Interventions
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2016-05-10
- Lead Sponsor
- Ottawa Hospital Research Institute
- Target Recruit Count
- 55
- Registration Number
- NCT00318812
- Locations
- π¨π¦
The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
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