Gabapentin

Generic Name: Gabapentin

Brand Names: Gralise, Neurontin

Drug Type: Small Molecule

Chemical Formula: C_₉H_₁₇NO_₂

CAS Number: 60142-96-3

Unique Ingredient Identifier: 6CW7F3G59X

Background: Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...

Indication: In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...

Associated Conditions: Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia

Associated Therapies: -

Clinical Trials

Gabapentin Versus Loratadine in Uremic Pruritus

Phase 4

Completed

Conditions: Pruritus
Uremia
Chronic Kidney Diseases

Interventions: Drug: Loratadine
Drug: Gabapentin

First Posted Date: 2023-03-02

Last Posted Date: 2023-03-16

Lead Sponsor: King Edward Medical University

Target Recruit Count: 64

Registration Number: NCT05750875

Locations: 🇵🇰
King Edward Medical University/Mayo Hospital, Lahore, Punjab, Pakistan

Melatonin vs Gabapentin for Post Trauma Surgery

Not Applicable

Recruiting

Conditions: Anxiety, Preoperarative

Interventions: Drug: Melatonin 6 MG
Drug: Gabapentin

First Posted Date: 2023-01-26

Last Posted Date: 2023-01-26

Lead Sponsor: All India Institute of Medical Sciences, New Delhi

Target Recruit Count: 70

Registration Number: NCT05699876

Locations: 🇮🇳
Aiims, New Delhi, Delhi, India

Glutamate Inhibitors in Glioblastoma

Phase 1

Recruiting

Conditions: Glioblastoma

Interventions: Drug: Temozolomide
Drug: Gabapentin
Radiation: Radiotherapy
Drug: Sulfasalazine
Drug: Memantine

First Posted Date: 2022-12-23

Last Posted Date: 2024-05-10

Lead Sponsor: University of Zurich

Target Recruit Count: 120

Registration Number: NCT05664464

Locations: 🇨🇭
University Hospital Zurich, Zürich, Zurich, Switzerland

Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery

Phase 4

Recruiting

Conditions: Pelvic Organ Prolapse
Perioperative/Postoperative Complications

Interventions: Drug: Gabapentin Placebo
Drug: Gabapentin

First Posted Date: 2022-12-21

Last Posted Date: 2024-06-28

Lead Sponsor: Joseph Kowalski

Target Recruit Count: 110

Registration Number: NCT05658887

Locations: 🇺🇸
University of Iowa, Iowa City, Iowa, United States

Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty

Phase 4

Completed

Conditions: Anesthesia

Interventions: Drug: Dexmedetomidine
Drug: Gabapentin

First Posted Date: 2022-11-25

Last Posted Date: 2023-08-30

Lead Sponsor: Ain Shams University

Target Recruit Count: 153

Registration Number: NCT05626998

Locations: 🇪🇬
faculty of medicine, Ain Shams University, Cairo, Egypt

Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

Phase 3

Active, not recruiting

Conditions: Post Operative Nausea and Vomiting
Morbid Obesity
Sleeve Gastrectomy

Interventions: Drug: Gabapentin
Drug: Ondansetron 8mg

First Posted Date: 2022-11-17

Last Posted Date: 2024-11-27

Lead Sponsor: Tanta University

Target Recruit Count: 100

Registration Number: NCT05620641

Locations: 🇪🇬
Gastrointestinal and Laparoscopic Surgery Unit, General Surgery Department, Tanta University Hospital, Tanta, Egypt, Tanta, Gharbiya, Egypt

Effect of Gabapentin on Post-Operative Pain in Minimally Invasive Sacrocolpopexy

Early Phase 1

Completed

Conditions: Post Operative Pain

Interventions: Drug: Placebo
Drug: Gabapentin

First Posted Date: 2022-11-08

Last Posted Date: 2024-12-06

Lead Sponsor: University of Oklahoma

Target Recruit Count: 40

Registration Number: NCT05609682

Locations: 🇺🇸
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

A Single Preoperative Dose of Gabapentin to Decreases Postoperative Pain in Ambulatory Anal Surgeries

Early Phase 1

Completed

Conditions: Pain, Postoperative

Interventions: Drug: Gabapentin

First Posted Date: 2022-09-09

Last Posted Date: 2023-03-16

Lead Sponsor: Minia University

Target Recruit Count: 50

Registration Number: NCT05533684

Locations: 🇪🇬
Sarah Omar, Minya, Egypt

Effect of PP-01 on Cannabis Withdrawal Syndrome

Phase 2

Completed

Conditions: Cannabis Withdrawal

Interventions: Combination Product: PP-01 High Dose
Combination Product: PP-01 Low Dose
Drug: Placebo
Drug: Nabilone
Drug: Gabapentin

First Posted Date: 2022-08-10

Last Posted Date: 2024-08-16

Lead Sponsor: PleoPharma, Inc.

Target Recruit Count: 234

Registration Number: NCT05494437

Locations: 🇺🇸
Pahl Pharmaceutical Professionals LLC, Oklahoma City, Oklahoma, United States
🇺🇸
Pillar Clinical Research, LLC, Chicago, Illinois, United States
🇺🇸
Behavioral Research Specialists, LLC, Glendale, California, United States

and more 15 locations

Gabapentin to Reduce Alcohol and Improve Viral Load Suppression

Phase 2

Recruiting

Conditions: HIV
Heavy Drinking

Interventions: Drug: Placebo
Drug: Gabapentin

First Posted Date: 2022-07-05

Last Posted Date: 2024-05-22

Lead Sponsor: Boston Medical Center

Target Recruit Count: 300

Registration Number: NCT05443555

Locations: 🇺🇬
Mbarara Regional Referral Hospital (MRRH): Immune Suppression Syndrome HIV, Mbarara, Uganda

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