Gabapentin

Generic Name
Gabapentin
Brand Names
Gralise, Neurontin
Drug Type
Small Molecule
Chemical Formula
C9H17NO2
CAS Number
60142-96-3
Unique Ingredient Identifier
6CW7F3G59X
Background

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...

Indication

In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...

Associated Conditions
Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia
Associated Therapies
-

Gabapentin for Carpal Tunnel Syndrome

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-08-30
Last Posted Date
2007-10-31
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
150
Registration Number
NCT00137735
Locations
🇭🇰

Prince of Wales Hospital, Shatin, New Territories, Hong Kong

🇭🇰

North District Hospital, Sheung Shui, New Territories, Hong Kong

Gabapentin for the Treatment of Hot Flashes in Menopausal Women

Phase 3
Completed
Conditions
First Posted Date
2005-05-30
Last Posted Date
2011-05-23
Lead Sponsor
North Toronto Primary Care Research Network
Target Recruit Count
200
Registration Number
NCT00112138
Locations
🇨🇦

The Scarborough Hospital, Scarborough, Ontario, Canada

Chronic Low Back Pain Research Project

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-04-18
Last Posted Date
2014-02-10
Lead Sponsor
US Department of Veterans Affairs
Target Recruit Count
108
Registration Number
NCT00108550
Locations
🇺🇸

VA San Diego Healthcare System, San Diego, San Diego, California, United States

Gabapentin With or Without Antidepressants in Treating Hot Flashes in Women Who Have Had Breast Cancer or Have Concerns About Taking Hormone Therapy

First Posted Date
2004-07-12
Last Posted Date
2016-07-14
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
118
Registration Number
NCT00087399
Locations
🇺🇸

Bismarck Cancer Center, Bismarck, North Dakota, United States

🇺🇸

John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital, Allentown, Pennsylvania, United States

🇺🇸

Galesburg Clinic, Galesburg, Illinois, United States

and more 159 locations

Gabapentin to Treat Itch in Patients With Liver Disease

First Posted Date
2003-04-16
Last Posted Date
2017-10-13
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
15
Registration Number
NCT00058890
Locations
🇺🇸

Columbia University College of Physicians and Surgeons, New York, New York, United States

Gabapentin in Fibromyalgia Trial (GIFT)

Phase 2
Completed
Conditions
First Posted Date
2003-03-31
Last Posted Date
2007-12-19
Lead Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Target Recruit Count
150
Registration Number
NCT00057278
Locations
🇺🇸

University of Cincinnati College of Medicine, Department of Psychiatry (must live in the Cincinnati, OH area), Cincinnati, Ohio, United States

🇺🇸

McLean Hospital/Harvard Medical School (must live in the Boston, MA area), Belmont, Massachusetts, United States

🇺🇸

Newton-Wellesley Hospital (must live in the Boston, MA area), Newton, Massachusetts, United States

Gabapentin in Treating Hot Flashes in Patients With Prostate Cancer

Phase 3
Completed
Conditions
Interventions
First Posted Date
2003-01-27
Last Posted Date
2016-06-28
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
223
Registration Number
NCT00028574
Locations
🇺🇸

Mobile Infirmary Medical Center, Mobile, Alabama, United States

🇺🇸

Eureka Community Hospital, Eureka, Illinois, United States

🇺🇸

Graham Hospital, Canton, Illinois, United States

and more 162 locations

Gabapentin For the Control of Hot Flashes in Women With Breast Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-10-15
Lead Sponsor
Gary Morrow
Registration Number
NCT00022074
Locations
🇺🇸

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

🇺🇸

CCOP - Northern New Jersey, Hackensack, New Jersey, United States

🇺🇸

MBCCOP - Gulf Coast, Mobile, Alabama, United States

and more 15 locations

Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2003-01-27
Last Posted Date
2016-07-04
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
100
Registration Number
NCT00027963
Locations
🇺🇸

CentraCare Health Plaza, Saint Cloud, Minnesota, United States

🇨🇦

Allan Blair Cancer Centre, Regina, Saskatchewan, Canada

🇺🇸

Mayo Clinic, Jacksonville, Florida, United States

and more 20 locations

Specific Interventions for Agitation in Alzheimer's Disease

Not Applicable
Completed
Conditions
First Posted Date
2001-07-05
Last Posted Date
2009-01-21
Lead Sponsor
US Department of Veterans Affairs
Registration Number
NCT00018291
Locations
🇺🇸

Palo Alto VA Health Care System, Menlo Park, California, United States

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