Bisacodyl
- Generic Name
- Bisacodyl
- Brand Names
- Alophen Reformulated Jan 2008, Bi-peglyte, Bisac-evac, Carters Little Pills, Dulcolax, Fleet Mineral Oil, Gavilyte-H and Bisacodyl
- Drug Type
- Small Molecule
- Chemical Formula
- C22H19NO4
- CAS Number
- 603-50-9
- Unique Ingredient Identifier
- 10X0709Y6I
- Background
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
- Indication
Bisacodyl is indicated to relieve occasional constipation and irregularity.
- Associated Conditions
- Bowel movement irregularity, Constipation, Occasional Constipation
- Associated Therapies
- Bowel preparation therapy
Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Day Before PicoPrep
- Conditions
- Bowel Preparation
- Interventions
- First Posted Date
- 2010-02-23
- Last Posted Date
- 2012-10-30
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 603
- Registration Number
- NCT01073943
- Locations
- 🇺🇸
Florida Clinical Research Group, Clearwater, Florida, United States
🇺🇸Gastroenterology Research Consultants of Greater Cincinnati, Cincinnati, Ohio, United States
🇺🇸Investigational site, Hollywood, Florida, United States
Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
- Conditions
- Bowel Preparation
- Interventions
- First Posted Date
- 2010-02-23
- Last Posted Date
- 2013-02-12
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 608
- Registration Number
- NCT01073930
- Locations
- 🇺🇸
Louisiana Research Center LLC, Shreveport, Louisiana, United States
🇺🇸Indiana University Hospital, Indianapolis, Indiana, United States
🇺🇸Piedmont Medical Research Associates, Winston-Salem, North Carolina, United States
Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation
- Conditions
- Preparation for Colonoscopy
- Interventions
- First Posted Date
- 2010-02-05
- Last Posted Date
- 2013-11-18
- Lead Sponsor
- Gastroenterology Services, Ltd.
- Target Recruit Count
- 600
- Registration Number
- NCT01063049
- Locations
- 🇺🇸
Gastroenterology Services, Downers Grove, Illinois, United States
Bisacodyl Use in the Post-operative Care of Obstetrical/Gynecological (OB/GYN) Patients
- Conditions
- Postoperative Nausea and VomitingAbdominal Pain
- Interventions
- Drug: placebo
- First Posted Date
- 2009-11-11
- Last Posted Date
- 2014-01-20
- Lead Sponsor
- The Cooper Health System
- Target Recruit Count
- 285
- Registration Number
- NCT01011426
- Locations
- 🇺🇸
Cooper University Hospital, Camden, New Jersey, United States
A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy
- Conditions
- Colonoscopy
- Interventions
- First Posted Date
- 2009-08-06
- Last Posted Date
- 2012-11-30
- Lead Sponsor
- Brooke Army Medical Center
- Target Recruit Count
- 425
- Registration Number
- NCT00953017
- Locations
- 🇺🇸
Brooke Army Medical Center, San Antonio, Texas, United States
Dulcolax vs Placebo in Functional Constipation
- First Posted Date
- 2007-09-06
- Last Posted Date
- 2014-01-15
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 368
- Registration Number
- NCT00526097
- Locations
- 🇬🇧
122.56.44011 Boehringer Ingelheim Investigational Site, Bedworth, United Kingdom
🇬🇧122.56.44032 Boehringer Ingelheim Investigational Site, Addlestone, United Kingdom
🇬🇧122.56.44018 Boehringer Ingelheim Investigational Site, Ash Vale, Aldershot, United Kingdom
Randomized Clinical Trial of Bisacodyl Versus Placebo on Postoperative Bowel Motility in Elective Colorectal Surgery
- First Posted Date
- 2007-07-31
- Last Posted Date
- 2007-07-31
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 200
- Registration Number
- NCT00509327
- Locations
- 🇨🇭
Department of Surgery, Triemli Hospital, Zurich, Switzerland, Zurich, Switzerland
A Randomized Controlled Trial Comparing Picosalax and Oral Sodium Phosphate for Colon Cleansing Prior to Colonoscopy
- Conditions
- Colonoscopy
- Interventions
- First Posted Date
- 2006-12-12
- Last Posted Date
- 2015-09-22
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 315
- Registration Number
- NCT00410215
- Locations
- 🇨🇦
Hotel Dieu Hospital, Kingston, Ontario, Canada
Drug Development Updates
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