Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wal...
Terbinafine hydrochloride is indicated to treat fungal skin and nail infections caused by Trichophyton species, Microsporum canis, Epidermophyton floccosum, and Tinea species. Terbinafine hydrochloride also treats yeast infections of the skin caused by Candida species and Malassezia furfur.
Amsterdam UMC, Amsterdam, Noord-Holland, Netherlands
Cmh Abbottabad, Abbottābād, Khyber Pakhtunkhwa, Pakistan
Kuchnir Dermatology & Dermatologic Surgery, Milford, Massachusetts, United States
Hamilton Health Sciences / McMaster University, Hamilton, Ontario, Canada
Vääksyn Lääkärikeskus, Vääksy, Finland
Cetero Research, San Antonio, Texas, United States
The Second Affiliated Hospital of Sun Yat-sen University Guangzhou, Guangdong, China
Chinese Academy of Medical Sciences, Jiangsu, China
Peking University First Hospital, Beijing, China
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