Glycerol phenylbutyrate
- Generic Name
- Glycerol phenylbutyrate
- Brand Names
- Ravicti
- Drug Type
- Small Molecule
- Chemical Formula
- C33H38O6
- CAS Number
- 611168-24-2
- Unique Ingredient Identifier
- ZH6F1VCV7B
- Background
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
- Indication
Glycerol phenylbutyrate is a nitrogen-binding agent for the chronic management of adult and pediatric patients ≥2 years of age with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.
- Associated Conditions
- Disorders of urea cycle metabolism
- Associated Therapies
- -
Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain
- First Posted Date
- 2014-01-27
- Last Posted Date
- 2022-04-25
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 38
- Registration Number
- NCT02046434
- Locations
- 🇺🇸
University of Colorado Denver Anschutz Medical Center, Aurora, Colorado, United States
Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease
- Conditions
- Byler Disease
- First Posted Date
- 2013-09-24
- Last Posted Date
- 2013-09-24
- Lead Sponsor
- University of Pittsburgh
- Registration Number
- NCT01949766
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