Alfacalcidol

Generic Name
Alfacalcidol
Brand Names
One-alpha
Drug Type
Small Molecule
Chemical Formula
C27H44O2
CAS Number
41294-56-8
Unique Ingredient Identifier
URQ2517572
Background

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacologi...

Indication

Alfacalcidol is indicated in adult patients with chronic renal failure for the management of hypocalcemia, secondary hyperparathyroidism, or osteodystrophy.
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Associated Conditions
Hypocalcemia, Hypophosphatemic Rickets, Nutritional Rickets, Osteodystrophy, Osteomalacia, Rickets, Secondary Hyperparathyroidism (SHPT), Hypophosphatemic osteomalacia
Associated Therapies
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