Tislelizumab

Generic Name
Tislelizumab
Brand Names
Tevimbra, Tizveni
Drug Type
Biotech
Chemical Formula
-
CAS Number
1858168-59-8
Unique Ingredient Identifier
0KVO411B3N
Background

Tislelizumab is under investigation in clinical trial NCT02660034 (The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Subjects With Advanced Solid Tumors).

Indication

⑴用于治疗至少经过二线系统化疗的复发或难治性经典型霍奇金淋巴瘤(R/R cHL)患者。

⑵用于治疗局部晚期或转移性尿路上皮癌。

⑶联合化疗用于治疗一线晚期非鳞状非小细胞肺癌(NSCLC)患者。

⑷用于治疗既往接受过治疗的不可切除肝细胞癌患者。

⑸用于治疗晚期恶性实体瘤

Associated Conditions
-
Associated Therapies
-

The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC

First Posted Date
2022-04-25
Last Posted Date
2022-12-29
Lead Sponsor
Fifth Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
25
Registration Number
NCT05343325
Locations
🇨🇳

Zhigang Liu, Dongguan, China

🇨🇳

Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China

Phase I/II Study of the Combination of Irinotecan and POF (POFI) and Tislelizumab

First Posted Date
2022-04-08
Last Posted Date
2023-09-18
Lead Sponsor
Fujian Cancer Hospital
Target Recruit Count
20
Registration Number
NCT05319639
Locations
🇨🇳

Fujian cancer hospital, Fuzhou, Fujian, China

SBRT Followed by Neoadjuvant Immunochemotherapy in Resectable Stage II to III Non-small Cell Lung Cancer

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-04-08
Last Posted Date
2024-01-16
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
46
Registration Number
NCT05319574
Locations
🇨🇳

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

TAS-102 Combined With Bevacizumab and Tislelizumab Third-line or Above in the Treatment of Liver Metastasis in Colorectal Cancer

First Posted Date
2022-04-06
Last Posted Date
2022-08-23
Lead Sponsor
Fujian Cancer Hospital
Target Recruit Count
25
Registration Number
NCT05314101
Locations
🇨🇳

FujianCH, Fuzhou, Fujian, China

Oncolytic Virotherapy Plus PD-1 Inhibitor and Lenvatinib for Patients With Advanced Pancreatic Cancer

First Posted Date
2022-03-31
Last Posted Date
2023-06-27
Lead Sponsor
Fudan University
Target Recruit Count
25
Registration Number
NCT05303090
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, China

Oncolytic Virotherapy Plus PD-1 Inhibitor for Patients With Refractory Malignant Ascites

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2022-03-31
Last Posted Date
2023-04-12
Lead Sponsor
Fudan University
Target Recruit Count
25
Registration Number
NCT05303844
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, China

Study of Chemotherapy and PD-1 Inhibitor Combination With Anti-angiogenesis to Treat Elderly Lung Cancer

First Posted Date
2022-03-10
Last Posted Date
2022-07-13
Lead Sponsor
Tianjin Medical University Cancer Institute and Hospital
Target Recruit Count
30
Registration Number
NCT05273814
Locations
🇨🇳

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China

Treatment of Relapsed or Refractory Diffuse Large B Cell Lymphoma With Ociperlimab (BGB A1217) in Combination With Tislelizumab (BGB A317) or Rituximab

First Posted Date
2022-03-04
Last Posted Date
2024-10-26
Lead Sponsor
BeiGene
Target Recruit Count
53
Registration Number
NCT05267054
Locations
🇨🇳

Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing, China

🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

🇨🇳

Beijing Hospital, Beijing, Beijing, China

and more 13 locations
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