Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

The Effects of Serratus Anterior Plane Block on Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery

Not Applicable

Completed

Conditions: Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery

Interventions: Drug: Ropivacaine
Drug: Normal Saline

First Posted Date: 2014-12-08

Last Posted Date: 2019-02-18

Lead Sponsor: Yonsei University

Target Recruit Count: 90

Registration Number: NCT02311517

Locations: 🇰🇷
Severance Hospital, Seoul, Korea, Republic of

Fascia Iliaca Block for Post-Operative Pain Control After Total Hip Arthroplasty

Phase 4

Terminated

Conditions: Osteoarthritis of the Hip

Interventions: Drug: Ropivacaine
Drug: Saline

First Posted Date: 2014-11-24

Last Posted Date: 2017-02-09

Lead Sponsor: The Christ Hospital

Target Recruit Count: 72

Registration Number: NCT02299271

Locations: 🇺🇸
The Christ Hospital, Cincinnati, Ohio, United States

Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain

Not Applicable

Withdrawn

Conditions: Low Back Pain

Interventions: Device: ReLeaf catheter
Drug: Saline
Drug: Ropivacaine
Drug: Morphine
Drug: Oxycodone

First Posted Date: 2014-11-18

Last Posted Date: 2016-01-22

Lead Sponsor: Vital 5, LLC

Registration Number: NCT02293525

Effect of a Lateral Nerve of the Thigh Block on Postoperative Pain After Total Hip Replacement Surgery

Phase 4

Completed

Conditions: Pain, Postoperative
Anesthesia, Conduction
Arthroplasty, Replacement, Hip

Interventions: Drug: Placebo
Drug: Ropivacaine
Device: An ultrasound-guided Nervus cutaneous femoral lateralis blockade will be given postoperatively

First Posted Date: 2014-11-13

Last Posted Date: 2014-11-13

Lead Sponsor: Daniel Hägi-Pedersen

Target Recruit Count: 100

Registration Number: NCT02289937

Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section

Phase 4

Conditions: Postoperative Pain

Interventions: Drug: Ropivacaine
Drug: Morphine

First Posted Date: 2014-10-31

Last Posted Date: 2014-10-31

Lead Sponsor: Central Hospital, Nancy, France

Target Recruit Count: 150

Registration Number: NCT02279628

Locations: 🇫🇷
Maternité Régionale Universitaire (MRU), Nancy, Lorraine, France

Comparison of Regimens MPIB, CIPCEA, PCEA

Phase 3

Active, not recruiting

Conditions: Breakthrough Pain

Interventions: Device: epidural delivery system
Drug: Ropivacaine
Drug: Fentanyl

First Posted Date: 2014-10-30

Last Posted Date: 2024-10-09

Lead Sponsor: KK Women's and Children's Hospital

Target Recruit Count: 839

Registration Number: NCT02278601

Locations: 🇸🇬
KK Women's and Children's Hospital, Singapore, Singapore

Effective Pain Management of Interscalene Blocks During Shoulder Surgery

Not Applicable

Completed

Conditions: Primary Osteoarthritis, Unspecified Shoulder

Interventions: Drug: Ropivacaine

First Posted Date: 2014-10-17

Last Posted Date: 2018-10-26

Lead Sponsor: TriHealth Inc.

Target Recruit Count: 76

Registration Number: NCT02267044

Locations: 🇺🇸
Good Samaritan Hospital, Cincinnati, Ohio, United States

Intra-Peritoneal Local Anaesthesia After Cytoreductive Surgery

Phase 3

Completed

Conditions: Pain

Interventions: Drug: Saline
Drug: Ropivacaine

First Posted Date: 2014-10-03

Last Posted Date: 2019-01-15

Lead Sponsor: Göteborg University

Target Recruit Count: 40

Registration Number: NCT02256228

Locations: 🇸🇪
Dept. of Gynecological Surgery and Anesthesia and Intensive Care, Sahlgrenska University Hospital, Goteborg, Sweden

Transmuscular Quadratus Lumborum Block for Laparoscopic Cholecystectomy

Not Applicable

Withdrawn

Conditions: Cholecystitis
Pain

Interventions: Drug: saline
Drug: Ropivacaine

First Posted Date: 2014-08-26

Last Posted Date: 2015-07-22

Lead Sponsor: Jens Borglum Neimann

Registration Number: NCT02225418

Locations: 🇩🇰
Bispebjerg Hospital, Copenhagen, Denmark

The Effect of Dexmedetomidine on Brachial Plexus Block for Shoulder Surgery

Phase 2

Completed

Conditions: Shoulder Pain
Nerve Pain

Interventions: Drug: Ropivacaine
Drug: Dexmedetomidine
Drug: Normal Saline

First Posted Date: 2014-08-25

Last Posted Date: 2017-11-06

Lead Sponsor: Women's College Hospital

Target Recruit Count: 99

Registration Number: NCT02225054

Locations: 🇨🇦
Women's College Hospital, Toronto, Ontario, Canada

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