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Clobetasol propionate

Generic Name
Clobetasol propionate
Brand Names
Clobex, Clodan, Dermovate, Impeklo, Impoyz, Olux, Temovate, Tovet
Drug Type
Small Molecule
Chemical Formula
C25H32ClFO5
CAS Number
25122-46-7
Unique Ingredient Identifier
779619577M

Overview

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.

Background

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.

Indication

Clobetasol propionate is indicated to treat moderate to severe plaque psoriasis as well as inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.

Associated Conditions

  • Alopecia
  • Severe Plaque psoriasis
  • Corticosteroid responsive, Inflammatory Dermatosis
  • Corticosteroid responsive, pruritic Dermatosis
  • Moderate Plaque psoriasis
  • Moderate Scalp Psoriasis
  • Severe Scalp Psoriasis

FDA Approved Products

Clobetasol Propionate
Manufacturer:Encube Ethicals Private Limited
Route:TOPICAL
Strength:0.5 mg in 1 g
Approved: 2023/12/22
NDC:21922-017
Clobetasol Propionate
Manufacturer:Amneal Pharmaceuticals NY LLC
Route:TOPICAL
Strength:0.05 g in 100 mL
Approved: 2021/03/30
NDC:69238-1732
Temovate Scalp Application
Manufacturer:PharmaDerm, A division of Fougera Pharmaceuticals Inc.
Route:TOPICAL
Strength:0.5 mg in 1 mL
Approved: 2012/07/06
NDC:0462-0269
clobetasol propionate
Manufacturer:Padagis Israel Pharmaceuticals Ltd
Route:TOPICAL
Strength:0.05 g in 100 mL
Approved: 2023/07/31
NDC:45802-961
Clobetasol Propionate
Manufacturer:Rebel Distributors Corp
Route:TOPICAL
Strength:0.5 mg in 1 mL
Approved: 2006/10/25
NDC:21695-358

Singapore Approved Products

MEDODERMONE OINTMENT 0.05%
Manufacturer:MEDOCHEMIE LTD (COGOLS FACILITY)
Form:OINTMENT
Strength:0.05% w/w
Online:Yes
Approved: 1991/08/27
Approval:SIN06530P
DERMOVATE OINTMENT 0.05% w/w
Manufacturer:GLAXO WELLCOME OPERATIONS, Delpharm Poznan S.A.
Form:OINTMENT
Strength:0.05% w/w
Online:Yes
Approved: 1990/07/12
Approval:SIN04933P
CLODERM CREAM 0.05% w/w
Manufacturer:HOE PHARMACEUTICALS SDN BHD
Form:CREAM
Strength:0.5 mg/g
Online:Yes
Approved: 1998/10/10
Approval:SIN10241P
Clobex Lotion 0.05%
Manufacturer:DPT Laboratories, Ltd
Form:LOTION
Strength:0.05%
Online:Yes
Approved: 2007/06/14
Approval:SIN13291P
DERMOSOL CREAM 0.5 mg/g
Manufacturer:Y S P INDUSTRIES (M) SDN BHD
Form:CREAM
Strength:0.5 mg/g
Online:Yes
Approved: 1998/10/26
Approval:SIN10297P

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