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Molibresib

Generic Name
Molibresib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C22H22ClN5O2
CAS Number
1260907-17-2
Unique Ingredient Identifier
5QIO6SRZ2R
Background

Molibresib is under investigation in clinical trial NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory Hematologic Malignancies).

Associated Conditions
-
Associated Therapies
-

Testing of the Addition of a New Anti-cancer Drug, Molibresib, to Chemotherapy Treatment (Etoposide and Cisplatin) for Patients With NUT Carcinoma

Phase 1
Withdrawn
Conditions
Unresectable NUT Carcinoma
Metastatic NUT Carcinoma
Interventions
First Posted Date
2019-10-04
Last Posted Date
2020-09-28
Lead Sponsor
National Cancer Institute (NCI)
Registration Number
NCT04116359

Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas

Phase 1
Withdrawn
Conditions
Advanced Lymphoma
Ann Arbor Stage III T-Cell Non-Hodgkin Lymphoma
Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphoma
Refractory Malignant Solid Neoplasm
Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma
Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma
Refractory Lymphoma
Refractory T-Cell Non-Hodgkin Lymphoma
Stage II Pancreatic Cancer AJCC v8
Stage IIA Pancreatic Cancer AJCC v8
Interventions
First Posted Date
2019-04-24
Last Posted Date
2020-09-28
Lead Sponsor
National Cancer Institute (NCI)
Registration Number
NCT03925428
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