Cefixime

Generic Name
Cefixime
Brand Names
Suprax
Drug Type
Small Molecule
Chemical Formula
C16H15N5O7S2
CAS Number
79350-37-1
Unique Ingredient Identifier
XZ7BG04GJX
Background

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results fro...

Indication

For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-l...

Associated Conditions
Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae, Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenzae, Bacterial Sinusitis, Community Acquired Pneumonia (CAP), Gonorrhea of anus, Lyme Disease, Salmonella Infections, Shigella Infection, Streptococcal Pharyngitis, Tonsillitis streptococcal, Uncomplicated Urinary Tract Infections, Bacterial otitis media, Bacterial rhinosinusitis, Disease caused by Salmonella typhi, Uncomplicated Gonorrhea
Associated Therapies
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Empiric Therapy of Mucopurulent Cervicitis (MPC)

First Posted Date
2010-02-19
Last Posted Date
2014-12-24
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
87
Registration Number
NCT01072136
Locations
🇺🇸

University of Mississippi - Infectious Diseases, Jackson, Mississippi, United States

🇺🇸

Harbor UCLA Medical Center - OBGYN - General Gynecology and Women's Health, Torrance, California, United States

🇺🇸

Louisiana Stte University - Health Sciences Center - Medicine, New Orleans, Louisiana, United States

and more 1 locations

A Pilot Study of the Addition of Bevacizumab to VOIT Regimen for Relapsed/Refractory Pediatric Solid Tumors

First Posted Date
2008-11-06
Last Posted Date
2021-02-10
Lead Sponsor
Children's Hospital Medical Center, Cincinnati
Target Recruit Count
13
Registration Number
NCT00786669
Locations
🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

First Posted Date
2004-10-08
Last Posted Date
2010-10-15
Lead Sponsor
Children's Hospital Los Angeles
Target Recruit Count
30
Registration Number
NCT00093353
Locations
🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Indiana University Cancer Center, Indianapolis, Indiana, United States

and more 10 locations

VNP20009 in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Therapy

First Posted Date
2004-02-25
Last Posted Date
2013-07-18
Lead Sponsor
Vion Pharmaceuticals
Registration Number
NCT00004216
Locations
🇺🇸

Mary Crowley Medical Research Center, Dallas, Texas, United States

🇺🇸

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

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