Fish oil

Generic Name
Fish oil
Brand Names
Omegaven
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
XGF7L72M0F
Background

Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.
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Indication

Under FDA approval, fish oil pharmaceuticals are typically products consisting of a combination of the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and are indicated primarily as an adjunct to diet to reduce triglyceride levels in adult patients with severe (>=500 mg/dL) hypertriglyceridemia .
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Associated Conditions
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Associated Therapies
Dietary and Nutritional Therapies, Nutritional supplementation, Parenteral Nutrition
uclahealth.org
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A low omega-6, omega-3 rich diet and fish oil may slow prostate cancer growth

A UCLA-led study in the Journal of Clinical Oncology found that a low omega-6, high omega-3 diet with fish oil supplements reduced prostate cancer cell growth in men on active surveillance, with a 15% decrease in the Ki-67 index compared to a 24% increase in the control group. Further research is needed to confirm long-term benefits.
nhlbi.nih.gov
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Omega-3s for heart health? Exploring potential benefits and risks

Fish oil omega-3 supplements' effectiveness in heart disease prevention is uncertain, with mixed clinical trial results and potential risks. VITAL trial showed no overall CVD risk reduction but significant benefits for low fish consumers, high-risk individuals, and African Americans. REDUCE-IT trial found icosapent ethyl reduced CVD risk by 25% in high-risk patients. Research continues on optimal omega-3 forms and mechanisms, with caution advised on high-dose supplement use.
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