Atropine
- Generic Name
- Atropine
- Brand Names
- Atnaa, Atropen, Busulfex, Donnatal, Duodote, Enlon-plus, Isopto Atropine, Lomotil, Minims Atropine Sulphate, Motofen, Phenohytro
- Drug Type
- Small Molecule
- Chemical Formula
- C17H23NO3
- CAS Number
- 51-55-8
- Unique Ingredient Identifier
- 7C0697DR9I
- Background
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine ...
- Indication
The intravenous, intramuscular, subcutaneous, intraosseous and endotracheal use of atropine is indicated for the temporary blockade of severe or life-threatening muscarinic effects. The intramuscular use of atropine in the form of a pen injector is indicated for the treatment of poisoning by susceptible organophosphorus nerve agents having cholinesterase act...
- Associated Conditions
- Amblyopia, Atrioventricular Heart-block, Bradycardia, Bronchospasm, Crying, Detrusor Hyperreflexia, Excessive bronchial secretion, Hypertonic uterine contraction, Hypertonicity of the small intestine, Ocular Inflammation, Parkinsonism, Peptic Ulcer, Poisoning by parasympathomimetics (cholinergics), Poisoning caused by mushrooms, Poisoning caused by organophosphate anticholinesterase nerve agents, Poisoning caused by organophosphorus pesticides, Pylorospasm, Rhinorrhoea, Sinus Bradycardia, Spasms, Toxic effect of organophosphate and carbamate, Hypermobility of the colon, Laughing, Life-threatening muscarinic side effects, Muscarinic side effects, Severe muscarinic side effects
- Associated Therapies
- -
Red Light Intervention on Myopic Progression
- First Posted Date
- 2022-01-24
- Last Posted Date
- 2022-10-12
- Target Recruit Count
- 104
- Registration Number
- NCT05203432
- Locations
- 🇨🇳
Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China
Assessing The Role Of Intravenous Lipid Emulsion As A Life Saving Therapy In Pesticides Toxicity
- First Posted Date
- 2021-08-16
- Last Posted Date
- 2022-08-16
- Lead Sponsor
- Aya Sabry Mohamed Mohamed
- Target Recruit Count
- 62
- Registration Number
- NCT05006638
- Locations
- 🇪🇬
Poison Control Center of Ain-Shams University hospitals, Cairo, Abbasya, Egypt
Defecation Patterns in Constipated Patients
- Conditions
- Interventions
- First Posted Date
- 2021-05-26
- Last Posted Date
- 2024-01-10
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 130
- Registration Number
- NCT04903470
- Locations
- 🇺🇸
University of California San Diego, La Jolla, California, United States
The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
- Conditions
- Interventions
- First Posted Date
- 2021-03-02
- Last Posted Date
- 2021-03-02
- Lead Sponsor
- University Hospital, Linkoeping
- Target Recruit Count
- 90
- Registration Number
- NCT04777383
- Locations
- 🇸🇪
University Hospital Linköping, Linköping, Östergötland, Sweden
The Effect and Safety of Different Doses of Atropine on Myopic Progression of Highly Myopic Children: Multi-centered Randomized Clinical Trial
- First Posted Date
- 2021-01-07
- Last Posted Date
- 2022-01-26
- Target Recruit Count
- 357
- Registration Number
- NCT04699357
- Locations
- 🇨🇳
Shanghai General Hospital, Shanghai, China
🇨🇳Shanghai Eye Disease Prevention & Treatment Center, Shanghai, Shanghai, China
🇨🇳Shanghai Ninth People's Hospital, Shanghai, China
The Personalized Chinese Herb Formulas Over Hypertensive Bradyarrhythmia
- Conditions
- Interventions
- First Posted Date
- 2020-08-10
- Last Posted Date
- 2020-08-10
- Lead Sponsor
- Jun Xiao
- Target Recruit Count
- 72
- Registration Number
- NCT04505228
- Locations
- 🇨🇳
The fifth Qingdao people's hospital, Qingdao, Shandong, China
Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise Training
- Conditions
- Interventions
- First Posted Date
- 2019-06-04
- Last Posted Date
- 2021-08-02
- Lead Sponsor
- Colorado State University
- Registration Number
- NCT03972683
- Locations
- 🇺🇸
Colorado State University, Fort Collins, Colorado, United States
Intrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CS
- First Posted Date
- 2019-04-30
- Last Posted Date
- 2019-10-07
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 60
- Registration Number
- NCT03932578
- Locations
- 🇪🇬
Mansoura University Hospital, Mansoura, Dakahlia, Egypt
Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom
- First Posted Date
- 2018-10-01
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- Belfast Health and Social Care Trust
- Target Recruit Count
- 289
- Registration Number
- NCT03690089
- Locations
- 🇬🇧
Centre for Living (Glasgow Caledonian University), Glasgow, United Kingdom
🇬🇧Anglia Ruskin University Eye Clinic, Cambridge, United Kingdom
🇬🇧Northern Ireland Clinical Research, Belfast, United Kingdom
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
- Conditions
- Interventions
- First Posted Date
- 2018-07-10
- Last Posted Date
- 2018-08-16
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 138
- Registration Number
- NCT03580889
- Locations
- 🇳🇵
Dr. BishnuPokharel, Dharān Bāzār, Sunsari, Nepal
Drug Development Updates
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