Budesonide

Generic Name
Budesonide
Brand Names
Airsupra, Breyna, Breztri, Cortiment, Entocort, Pulmicort, Pulmicort Turbuhaler, Rhinocort, Symbicort, Tarpeyo, Uceris, Jorveza, Kinpeygo
Drug Type
Small Molecule
Chemical Formula
C25H34O6
CAS Number
51333-22-3
Unique Ingredient Identifier
Q3OKS62Q6X
Background

Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.

Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product with formoterol.

Indication

Budesonide extended release capsules are indicated for the treatment and maintenance of mild to moderate Crohn’s disease. Various inhaled budesonide products are indicated for prophylactic therapy in asthma and to reduce exacerbations of COPD. A budesonide nasal spray is available over the counter for symptoms of hay fever and upper respiratory allergies. E...

Associated Conditions
Allergic Reaction, Allergic Rhinitis (AR), Asthma, Bronchoconstriction, Chronic Obstructive Pulmonary Disease (COPD), Collagenous Colitis, Crohn's Disease (CD), Eosinophilic Esophagitis, Exacerbation of asthma, Nasal Congestion, Nasal Polyps, Proteinuria, Pruritus, Rhino Sinusitis, Ulcerative Colitis, Vasomotor Rhinitis, Corticosteroid-responsive dermatoses, Mild Crohn’s Disease, Moderate Crohn’s Disease
Associated Therapies
Maintenance therapy

The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis

First Posted Date
2016-03-02
Last Posted Date
2019-09-03
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
80
Registration Number
NCT02696850
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Altitude Sickness Prevention and Efficacy of Comparative Treatments

First Posted Date
2015-11-13
Last Posted Date
2018-12-12
Lead Sponsor
Stanford University
Target Recruit Count
103
Registration Number
NCT02604173
Locations
🇺🇸

Owens Valley Lodge - White Mountain Research Station, Bishop, California, United States

The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery

First Posted Date
2015-09-29
Last Posted Date
2019-10-16
Lead Sponsor
University of Vermont Medical Center
Target Recruit Count
40
Registration Number
NCT02562924
Locations
🇺🇸

University of Vermont Medical Center, Burlington, Vermont, United States

Budesonide 9 mg Capsules in Active UC

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-09-15
Last Posted Date
2017-07-26
Lead Sponsor
Dr. Falk Pharma GmbH
Target Recruit Count
60
Registration Number
NCT02550418
Locations
🇩🇪

University of Schleswig-Holstein, Lübeck, Schleswig-Holstein, Germany

Small Airways Evaluation and Treatment

First Posted Date
2015-08-18
Last Posted Date
2015-08-18
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
90
Registration Number
NCT02526758
Locations
🇨🇳

Zhujiang Hospital, Guangzhou, Guangdong, China

Efficacy of Nebulized Pulmicort Respules in Primary Lung Cancer Patients With COPD

First Posted Date
2015-07-22
Last Posted Date
2015-07-22
Lead Sponsor
Xiuyi Zhi
Target Recruit Count
73
Registration Number
NCT02504801

A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma

First Posted Date
2015-05-18
Last Posted Date
2019-01-14
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
423
Registration Number
NCT02446418
Locations
🇩🇪

GSK Investigational Site, Magdeburg, Germany

Methylprednisolone Sodium Succinate in Treating Patients With Acute Graft-versus-Host Disease of the Gastrointestinal Tract

First Posted Date
2015-04-24
Last Posted Date
2018-08-02
Lead Sponsor
Wake Forest University Health Sciences
Registration Number
NCT02425813
Locations
🇺🇸

Comprehensive Cancer Center of Wake Forest University, Winston-Salem, North Carolina, United States

An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide

First Posted Date
2015-03-27
Last Posted Date
2022-05-06
Lead Sponsor
Puma Biotechnology, Inc.
Target Recruit Count
563
Registration Number
NCT02400476
Locations
🇺🇸

Compassionate Care Research Group Inc., Riverside, California, United States

🇺🇸

Emad Ibrahim, M.D., Inc., Redlands, California, United States

🇺🇸

The Oncology Institute of Hope and Innovation, Santa Ana, California, United States

and more 54 locations

The Effects of Inhaled Glucocorticoids on the Postmenopausal Skeleton

Phase 4
Withdrawn
Conditions
Interventions
First Posted Date
2015-02-06
Last Posted Date
2017-07-18
Lead Sponsor
Columbia University
Registration Number
NCT02357277
© Copyright 2024. All Rights Reserved by MedPath