Terbutaline
- Generic Name
- Terbutaline
- Brand Names
- Bricanyl
- Drug Type
- Small Molecule
- Chemical Formula
- C12H19NO3
- CAS Number
- 23031-25-6
- Unique Ingredient Identifier
- N8ONU3L3PG
- Background
Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.
Terbutaline was granted FDA approval on 25 March 1974.
- Indication
Terbutaline is indicated for prevention and reversal of bronchospasm in patients at least 12 years old, with asthma and reversible bronchospasm associated with bronchitis and emphysema.
- Associated Conditions
- Asthma, Bronchospasm, Chronic Cough (CC), Chronic Obstructive Pulmonary Disease (COPD), Cough, Premature Labour, Productive cough
- Associated Therapies
- Airway secretion clearance therapy
Randomized Controlled Trial of Intravenous Magnesium Sulfate Versus Terbutaline for Children in the Management of Acute Exacerbation of Asthma
- Conditions
- Acute Exacerbation of Asthma
- Interventions
- Drug: Magnesium Sulphate infusion
- First Posted Date
- 2024-10-04
- Last Posted Date
- 2024-10-04
- Lead Sponsor
- Muhammad Aamir Latif
- Target Recruit Count
- 120
- Registration Number
- NCT06626620
- Locations
- 🇵🇰
Nishtar Hospital, Multan, Punjab, Pakistan
The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2022-08-09
- Last Posted Date
- 2022-08-09
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 228
- Registration Number
- NCT05494307
Acute Tocolysis With Terbutaline for Suspected Fetal Distress
- First Posted Date
- 2022-04-13
- Last Posted Date
- 2022-04-13
- Lead Sponsor
- Hospital Kemaman
- Target Recruit Count
- 100
- Registration Number
- NCT05326269
- Locations
- 🇲🇾
Hospital Kemaman, Kuala Terengganu, Terengganu, Malaysia
Hot Flashes and Neurovascular Function in Women
- Conditions
- Hot FlashesMenopauseVasomotor System; Labile
- Interventions
- Other: Sympathoexcitatory stressors
- First Posted Date
- 2022-01-18
- Last Posted Date
- 2024-05-24
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 120
- Registration Number
- NCT05193968
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Terbutaline Sulfate in Adults With Asthma
- First Posted Date
- 2021-07-22
- Last Posted Date
- 2025-04-16
- Lead Sponsor
- Kanecia Obie Zimmerman
- Target Recruit Count
- 30
- Registration Number
- NCT04973345
- Locations
- 🇺🇸
University of Colorado, Aurora, Colorado, United States
🇺🇸University of Vermont, Burlington, Vermont, United States
Budesonide/Formoterol Turbuhaler® Versus Terbutaline Nebulization as Reliever Therapy in Children With Moderate Asthma Exacerbation
- Conditions
- Asthma in Children
- Interventions
- First Posted Date
- 2021-01-12
- Last Posted Date
- 2023-07-27
- Lead Sponsor
- Centre Hospitalier Intercommunal Creteil
- Target Recruit Count
- 102
- Registration Number
- NCT04705727
- Locations
- 🇫🇷
CHU Ambroise Paré, Boulogne-Billancourt, France
🇫🇷CHU Lille, Lille, France
🇫🇷Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France
The Combination of Terbutaline and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2020-07-22
- Last Posted Date
- 2020-07-22
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT04481282
- Locations
- 🇨🇳
Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, Beijing, China
In Utero Repair of Myelomeningocele: Atosiban Versus Terbutaline
- Conditions
- MyelomeningoceleTerbutaline Adverse ReactionPregnancy; Malformation Central Nervous System
- Interventions
- First Posted Date
- 2020-07-13
- Last Posted Date
- 2022-06-06
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 25
- Registration Number
- NCT04468568
- Locations
- 🇧🇷
Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Beta2-adrenergic Agonism and Muscle Remodelling
- Conditions
- HypertrophyPhysiologic HypertrophyPhysical Activity
- Interventions
- First Posted Date
- 2018-06-21
- Last Posted Date
- 2020-03-25
- Lead Sponsor
- Morten Hostrup, PhD
- Target Recruit Count
- 72
- Registration Number
- NCT03565302
- Locations
- 🇩🇰
August Krogh Building, Copenhagen, Denmark
Success of External Cephalic Version Study
- First Posted Date
- 2017-04-10
- Last Posted Date
- 2020-10-09
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 34
- Registration Number
- NCT03106753
- Locations
- 🇺🇸
Mount Sinai West, New York, New York, United States
Drug Development Updates
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