MedPath

PF-06305591

Generic Name
PF-06305591
Drug Type
Small Molecule
Chemical Formula
C15H22N4O
CAS Number
1449473-97-5
Unique Ingredient Identifier
G5Y3F1X9MU
Background

Pf 06305591 is under investigation in clinical trial NCT01776619 (Safety and Tolerability Study of Multiple Doses of PF-06305591).

Mechanism of Human Cold Pain Perception - Involvement of TRPA1, TRPM8, Nav1.7 and Nav1.8

Early Phase 1
Completed
Conditions
Pain
Interventions
Other: Room temperature
Other: Cold temperature
Drug: Lidocain
First Posted Date
2023-07-07
Last Posted Date
2024-03-15
Lead Sponsor
Medical University of Vienna
Target Recruit Count
36
Registration Number
NCT05935280
Locations
🇦🇹

Medical University of Vienna, Vienna, Austria

Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2013-03-18
Last Posted Date
2013-09-17
Lead Sponsor
Pfizer
Target Recruit Count
16
Registration Number
NCT01812265
Locations
🇧🇪

Pfizer Investigational Site, Bruxelles, Belgium

Effect Of PF-06305591 On Capsaicin And Capsaicin/Heat-Induced Neurogenic Flare

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
Other: Capsaicin challenge
First Posted Date
2013-02-25
Last Posted Date
2013-08-20
Lead Sponsor
Pfizer
Target Recruit Count
16
Registration Number
NCT01797796
Locations
🇧🇪

Pfizer Investigational Site, Brussels, Belgium

Safety and Tolerability Study of Multiple Doses of PF-06305591

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2013-01-28
Last Posted Date
2013-12-03
Lead Sponsor
Pfizer
Target Recruit Count
43
Registration Number
NCT01776619
Locations
🇧🇪

Pfizer Investigational Site, Brussels, Belgium

Study to Investigate the Safety, Tolerability, Pharmacokinetics of PF-06305591 in Healthy Male and Female Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2012-12-12
Last Posted Date
2013-05-23
Lead Sponsor
Pfizer
Target Recruit Count
30
Registration Number
NCT01747941
Locations
🇧🇪

Pfizer Investigational Site, Brussels, Belgium

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