Dimethicone

Generic Name
Dimethicone
Brand Names
A+d Diaper Rash, Alka-seltzer Heartburn Plus Gas Relief, Almacone, Carlesta, Dyna1199 with Dimethicone, Dynashield, Gelusil, Gold Bond Maximum Relief, Imodium Multi-symptom Relief, Maalox Plus, Mi-acid, Mi-acid Double Strength, Mintox Plus, Mylanta, Mylanta Tonight, Pediacare Gas Relief, Phazyme, Rash Relief Antibacterial, Rash Relief Antifungal, Rash Relief With Zinc Oxide, Rolaids Advanced, Titralac Plus
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
63148-62-9
Unique Ingredient Identifier
92RU3N3Y1O
Background

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. On skin, it is also observed to have moisturizing actions .

A study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing products .

Indication

Dimethicone is a colorless liquid with both cosmetic and therapeutic uses. It is used in topical creams and ointments to help distribute the active ingredients. Dimethicone is used as an anti-foaming agent, a hair and skin conditioner, and in the treatment of head lice and, as an anti-bloating/anti-flatulence agent , .

Associated Conditions
Acute Diarrhea, Aerophagy, Dry Skin, Duodenal Ulcer, Dyspepsia, Flatulence, Gastric Ulcer, Gastritis, Gastro-esophageal Reflux Disease (GERD), Hiatus Hernia, Pancreatic Insufficiency, Post Operative Gas, Pre-operative Gas, Stress Ulcers
Associated Therapies
Bowel preparation therapy, Carbohydrate Digestion, Digestive Aid, Fat Digestion, Protein Digestion

Effect of Premedication With Pronase on Mucosal Cleanliness During EGD

First Posted Date
2024-12-03
Last Posted Date
2024-12-03
Lead Sponsor
Changhai Hospital
Target Recruit Count
3000
Registration Number
NCT06713421
Locations
🇨🇳

Changhai hosipital, Shanghai, China

Parallel Group Trial to Evaluate the Efficacy and Safety of Loion® Compared to 10% Salicylic Acid in Patients With Chronic Psoriasis Capitis

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-08-02
Last Posted Date
2014-11-05
Lead Sponsor
G. Pohl-Boskamp GmbH & Co. KG
Target Recruit Count
90
Registration Number
NCT01914627
Locations
🇩🇪

University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany

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