Levothyroxine

Generic Name
Levothyroxine
Brand Names
Eltroxin, Ermeza, Euthyrox, Levo-T, Levothroid, Levoxyl, Np Thyroid, Synthroid, Thyquidity, Tirosint, Unithroid
Drug Type
Small Molecule
Chemical Formula
C15H11I4NO4
CAS Number
51-48-9
Unique Ingredient Identifier
Q51BO43MG4
Background

Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the thyroid hormones T (tetraio...

Indication

Levothyroxine is indicated as replacement therapy in primary (thyroidal), secondary (pituitary) and tertiary (hypothalamic) congenital or acquired hypothyroidism. It is also indicated as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.

Associated Conditions
Edematous Fibrosclerotic Panniculopathy (Cellulite), Hypothyroidism, Localized Adiposity, Myxedema coma, Euthyroid Goitre, Thyrotropin dependent Well-Differentiated Thyroid Cancer
Associated Therapies
-
Clinical Trials
Related News

Supplemental Thyroxine Treatment for Preterm Infants With Hypothyroxinemia

Not Applicable
Completed
Conditions
Hypothyroxinemia
Interventions
Drug: thyroxine
First Posted Date
2007-11-30
Last Posted Date
2013-06-04
Lead Sponsor
Tokyo Women's Medical University
Target Recruit Count
100
Registration Number
NCT00565890
Locations
🇯🇵

Maternal and Perinatal Center, Tokyo Women's Medical University, Tokyo, Japan

Metabolic Changes in Hypothyroid Patients

Not Applicable
Completed
Conditions
Hypothyroidism
Interventions
Drug: L-thyroxine
First Posted Date
2007-09-03
Last Posted Date
2008-02-12
Lead Sponsor
University of Aarhus
Target Recruit Count
22
Registration Number
NCT00524238
Locations
🇩🇰

Aarhus University Hospital, Aarhus, Denmark

The Effect of Levothyroxine on Arterial Stiffness and Lipid Profile in Patients With Subclinical Hypothyroidism

Not Applicable
Completed
Conditions
Subclinical Hypothyroidism
First Posted Date
2007-07-09
Last Posted Date
2007-07-09
Lead Sponsor
Assaf-Harofeh Medical Center
Target Recruit Count
34
Registration Number
NCT00498238

Combined Levothyroxine/Liothyronine Supplementation in Hypothyroid Patients With Brain Tumors

Not Applicable
Terminated
Conditions
Hypothyroidism
Brain Tumor
Interventions
Drug: Levothyroxine
Drug: Liothyronine
First Posted Date
2007-06-20
Last Posted Date
2013-06-24
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
12
Registration Number
NCT00488644
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy

First Posted Date
2006-10-16
Last Posted Date
2019-02-21
Lead Sponsor
The George Washington University Biostatistics Center
Target Recruit Count
1203
Registration Number
NCT00388297
Locations
🇺🇸

University of Utah Medical Center, Salt Lake City, Utah, United States

🇺🇸

Oregon Health & Sciences University, Portland, Oregon, United States

🇺🇸

Wayne State University, Detroit, Michigan, United States

and more 11 locations

Thyroid Hormone Dose Adjustment in Pregnancy

First Posted Date
2005-10-03
Last Posted Date
2016-12-23
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
48
Registration Number
NCT00230802
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Thyroxine Titration Study

Phase 4
Conditions
Hypothyroidism
First Posted Date
2005-05-25
Last Posted Date
2005-06-24
Lead Sponsor
Sir Charles Gairdner Hospital
Target Recruit Count
55
Registration Number
NCT00111735
Locations
🇦🇺

Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia

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