MedPath

Tesnatilimab

Generic Name
Tesnatilimab
Drug Type
Biotech
CAS Number
2242758-08-1
Unique Ingredient Identifier
2B860WP9F0
Background

Tesnatilimab is under investigation in clinical trial NCT04655807 (A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease).

A Study of JNJ-64304500 in Participants With Alopecia Areata

Phase 2
Withdrawn
Conditions
Alopecia Areata
Interventions
Drug: Placebo
First Posted Date
2021-02-05
Last Posted Date
2021-05-04
Lead Sponsor
Janssen Research & Development, LLC
Registration Number
NCT04740970
Locations
🇯🇵

The Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan

🇯🇵

Yamaguchi University Hospital, Ube, Japan

🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

and more 19 locations

A Study of JNJ-64304500 Following Subcutaneous Injection in Healthy Chinese Adult Participants

Phase 1
Withdrawn
Conditions
Healthy
Interventions
First Posted Date
2021-01-15
Last Posted Date
2021-09-01
Lead Sponsor
Janssen Research & Development, LLC
Registration Number
NCT04712006
Locations
🇨🇳

Peking University Third Hospital, Beijing, China

A Study to Compare Two Different Subcutaneously-administered JNJ-64304500 Formulations in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2020-12-14
Last Posted Date
2025-02-03
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
43
Registration Number
NCT04667052
Locations
🇺🇸

WCCT Global, LLC, Cypress, California, United States

A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease

Phase 2
Withdrawn
Conditions
Crohn Disease
Interventions
First Posted Date
2020-12-07
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Registration Number
NCT04655807
Locations
🇺🇸

Medisphere Medical Research Center, Llc, Evansville, Indiana, United States

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Subcutaneous Injection of JNJ-64304500 in Healthy Japanese and Caucasian Male Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2016-12-23
Last Posted Date
2025-02-03
Lead Sponsor
Janssen Pharmaceutical K.K.
Target Recruit Count
48
Registration Number
NCT03002025

Safety and Efficacy Study of JNJ-64304500 in Participants With Moderately to Severely Active Crohn's Disease

Phase 2
Completed
Conditions
Crohn Disease
Interventions
First Posted Date
2016-08-24
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
388
Registration Number
NCT02877134
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