Rasagiline

Generic Name
Rasagiline
Brand Names
Azilect, Rasagiline Mylan, Rasagiline ratiopharm
Drug Type
Small Molecule
Chemical Formula
C12H13N
CAS Number
136236-51-6
Unique Ingredient Identifier
003N66TS6T
Background

Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

Indication

For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.

Associated Conditions
Parkinson's Disease (PD)
Associated Therapies
-

Clinical Trial of Rasagiline in Levodopa-Treated Parkinson's Disease Patients With Motor Fluctuations

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-11-29
Last Posted Date
2013-09-13
Lead Sponsor
Chongqing Fortune Pharmaceutical Co., Ltd.
Target Recruit Count
268
Registration Number
NCT01736891
Locations
🇨🇳

CN006, Luzhou, China

🇨🇳

CN003, Guilin, China

🇨🇳

CN002, Chengdu, China

and more 5 locations

Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson's Disease

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-11-07
Last Posted Date
2021-11-09
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
170
Registration Number
NCT01723228
Locations
🇺🇸

Teva Investigational Site 003, Chicago, Illinois, United States

🇺🇸

Teva Investigational Site 016, La Jolla, California, United States

🇺🇸

Teva Investigational Site 004, Irvine, California, United States

and more 37 locations

Pharmacokinetic Properties of Rasagiline (Lu 00-773) in Healthy Young Chinese Men and Women

Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-07-30
Last Posted Date
2012-07-30
Lead Sponsor
H. Lundbeck A/S
Target Recruit Count
12
Registration Number
NCT01652313
Locations
🇨🇳

CN001, Beijing, China

Rasagiline in Early Parkinson's Disease Patients Not Treated With Levodopa in China

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-03-16
Last Posted Date
2014-12-23
Lead Sponsor
H. Lundbeck A/S
Target Recruit Count
130
Registration Number
NCT01556165
Locations
🇨🇳

CN005, Guangzhou, China

🇨🇳

CN011, Chengdu, China

🇨🇳

CN004, Hangzhou, China

and more 12 locations

Effect of BIA 9-1067 on Rasagiline Pharmacokinetics

Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-02-14
Last Posted Date
2015-08-20
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
24
Registration Number
NCT01532128
Locations
🇫🇷

BIOTRIAL, Rennes, France

Effect of Rasagiline on BIA 9-1067 Pharmacokinetics

Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-02-14
Last Posted Date
2015-08-20
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
25
Registration Number
NCT01532141
Locations
🇫🇷

BIOTRIAL, Rennes, France

A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic Therapy

First Posted Date
2011-12-22
Last Posted Date
2015-12-16
Lead Sponsor
Georgetown University
Target Recruit Count
34
Registration Number
NCT01497652
Locations
🇺🇸

Georgetown University Hospital, Washington, District of Columbia, United States

Effects of Rasagiline on Sleep Disturbances in Parkinson's Disease

First Posted Date
2011-09-28
Last Posted Date
2016-01-21
Lead Sponsor
Technische Universität Dresden
Target Recruit Count
30
Registration Number
NCT01442610
Locations
🇩🇪

Dresden University of Technology, Dept. of Neurology, Dresden, Germany

Emotion, Mood and Executive Function in Parkinson's Disease (PD)

First Posted Date
2011-06-30
Last Posted Date
2011-06-30
Lead Sponsor
St. Josef Hospital Bochum
Target Recruit Count
70
Registration Number
NCT01385735
Locations
🇩🇪

St. Josef Hospital, Bochum, Nordrhein-Westfalen, Germany

The Effect of Rasagiline on Cognition in Parkinson's Disease

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-06-27
Last Posted Date
2015-02-05
Lead Sponsor
Brown University
Target Recruit Count
50
Registration Number
NCT01382342
Locations
🇺🇸

Butler Hospital, Providence, Rhode Island, United States

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