MedPath

AST-120

Generic Name
AST-120

Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis

Phase 2
Terminated
Conditions
Pouchitis
Interventions
First Posted Date
2007-12-31
Last Posted Date
2014-06-18
Lead Sponsor
Ocera Therapeutics
Target Recruit Count
2
Registration Number
NCT00583531
Locations
🇺🇸

Mayo Clinic, Inflammatory Bowel Disease Clinic, Rochester, Minnesota, United States

Safety and Efficacy of AST-120 in Patients With Non-Constipating Irritable Bowel Syndrome

Phase 2
Completed
Conditions
Irritable Bowel Syndrome
Interventions
Drug: Celphere® CP-305
First Posted Date
2007-12-31
Last Posted Date
2014-06-18
Lead Sponsor
Ocera Therapeutics
Target Recruit Count
117
Registration Number
NCT00583128
Locations
🇺🇸

Chevy Chase Clinical Research, Chevy Chase, Maryland, United States

🇺🇸

Medical Center for Clinical Research, San Diego, California, United States

🇺🇸

Madeleine DuPree, MD, Boynton Beach, Florida, United States

and more 14 locations

Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy

Phase 2
Completed
Conditions
Hepatic Encephalopathy
Interventions
First Posted Date
2007-11-14
Last Posted Date
2014-05-30
Lead Sponsor
Ocera Therapeutics
Target Recruit Count
40
Registration Number
NCT00558038
Locations
🇺🇸

University of Massachusetts Medical School, Worchester, Massachusetts, United States

🇺🇸

McGuire VA Medical Center, Richmond, Virginia, United States

🇺🇸

Mount Sinai School of Medicine, New York, New York, United States

and more 13 locations

A Study of AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease Including Assessment of Quality of Life (EPPIC-2)

Phase 3
Completed
Conditions
Chronic Kidney Disease
Interventions
Drug: Placebo
First Posted Date
2007-07-13
Last Posted Date
2022-06-07
Lead Sponsor
Mitsubishi Tanabe Pharma Corporation
Target Recruit Count
1015
Registration Number
NCT00501046

A Study of AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease (EPPIC-1)

Phase 3
Completed
Conditions
Chronic Kidney Disease
Interventions
Drug: Placebo
First Posted Date
2007-07-13
Last Posted Date
2022-06-07
Lead Sponsor
Mitsubishi Tanabe Pharma Corporation
Target Recruit Count
1020
Registration Number
NCT00500682

Carbonaceous Oral Adsorbent's Effects on Progression of Chronic Kidney Disease

Phase 4
Completed
Conditions
Kidney Failure, Chronic
First Posted Date
2007-04-05
Last Posted Date
2007-10-18
Lead Sponsor
Institute for Health Outcomes and Process Evaluation Reseach
Target Recruit Count
450
Registration Number
NCT00456859
Locations
🇯🇵

iHope International, Tokyo, Japan

Safety and Efficacy of AST-120 in Mild to Moderate Crohn's Patients With Fistulas

Phase 3
Completed
Conditions
Inflammatory Bowel Disease
Intestinal Fistula
Interventions
First Posted Date
2006-05-03
Last Posted Date
2014-05-30
Lead Sponsor
Ocera Therapeutics
Target Recruit Count
191
Registration Number
NCT00321412
Locations
🇦🇹

Universitatsklinik fur Innere Medizin I der PMU, Salzburg, Austria

🇧🇪

University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium

🇺🇸

University of North Carolina, Chapel Hill, North Carolina, United States

and more 84 locations
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