Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Effect of Dexmedetomidine Preconditioning on Myocardial Ischemia-reperfusion Injury in Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass
- Conditions
- Interventions
- First Posted Date
- 2022-10-28
- Last Posted Date
- 2024-03-21
- Lead Sponsor
- Affiliated Hospital of Nantong University
- Target Recruit Count
- 64
- Registration Number
- NCT05598177
- Locations
- 🇨🇳
Affiliated Hospital Nantong University, Nantong, Jiangsu, China
The Effect of Intraperitoneal Injection of Magnesium Sulphate Versus Dexmedetomidine as an Adjuvant to Bupivacaine on Postoperative Analgesia in Patients Undergoing Abdominal Aortic Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-10-13
- Last Posted Date
- 2022-10-13
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 50
- Registration Number
- NCT05577260
- Locations
- 🇪🇬
Mansoura University,Mansoura University Hospitals, Mansoura, Dakahlia, Egypt
Dexmedetomidine in Off Pump Coronary Artery Bypass Grafting
- Conditions
- Interventions
- First Posted Date
- 2022-10-13
- Last Posted Date
- 2022-10-13
- Lead Sponsor
- Suez Canal University
- Target Recruit Count
- 36
- Registration Number
- NCT05577871
Fentanyl vs Dexmedetomidine for Arthriscopic Shoulder Intervention in Elderly.
- First Posted Date
- 2022-10-13
- Last Posted Date
- 2022-11-21
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 36
- Registration Number
- NCT05577117
- Locations
- 🇪🇬
Faculty of medicine Cairo university, Cairo, Egypt
Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty
- Conditions
- Interventions
- First Posted Date
- 2022-10-10
- Last Posted Date
- 2022-10-10
- Lead Sponsor
- Baskent University
- Target Recruit Count
- 50
- Registration Number
- NCT05572723
- Locations
- 🇹🇷
Baskent University Medical School, Ankara, Turkey
Safety Study of Dexmedetomidine in Elderly Under General Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2022-10-05
- Last Posted Date
- 2022-10-13
- Lead Sponsor
- Zhenjiang First People's Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT05567523
- Locations
- 🇨🇳
Zhenjiang First People's Hospital, Zhenjiang, Jiangsu, China
Dexmedetomidine and Magnesium Sulfate in Preventing Junctional Ectopic Tachycardia After Pediatric Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-09-26
- Last Posted Date
- 2024-04-18
- Lead Sponsor
- Kasr El Aini Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05554848
- Locations
- 🇪🇬
Kasralainy Faculty of Medicine, Cairo, Egypt
The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2022-09-01
- Last Posted Date
- 2022-09-07
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Target Recruit Count
- 60
- Registration Number
- NCT05525351
- Locations
- 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan
In Vitro Evaluation of Spontaneous and Oxytocin-induced Contractility of Pregnant Human Myometrium During Exposure to Dexmedetomidine
- Conditions
- Interventions
- First Posted Date
- 2022-08-23
- Last Posted Date
- 2024-02-26
- Target Recruit Count
- 28
- Registration Number
- NCT05511415
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
The Effects of Sedatives on Tobacco Use Disorder Version 2
- Conditions
- Interventions
- First Posted Date
- 2022-08-18
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 52
- Registration Number
- NCT05505630
- Locations
- 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Drug Development Updates
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