AGuIX
- Generic Name
- AGuIX
- Drug Type
- Biotech
- Background
AGuIX is an investigational brand product consisting of a polysiloxane matrix and gadolinium chelates. It is under development as a radiosensitizer to be used during radiation treatment of malignant glioma.
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
- Conditions
- Brain CancerBrain MetastasesLung CancerColorectal CancerGastrointestinal CancerSRSMelanomaBreast CancerHER2-positive Breast CancerSRT
- Interventions
- First Posted Date
- 2021-05-25
- Last Posted Date
- 2024-10-24
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 134
- Registration Number
- NCT04899908
- Locations
- 🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸Brigham and Women's Hospital, Boston, Massachusetts, United States
Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
- Conditions
- Non-small Cell Lung CancerUnresectable Pancreatic CancerAdvanced Pancreatic AdenocarcinomaDuctal Adenocarcinoma of the Pancreas
- Interventions
- Radiation: Radiotherapy
- First Posted Date
- 2021-03-09
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 100
- Registration Number
- NCT04789486
- Locations
- 🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸Brigham and Women's Hospital, Boston, Massachusetts, United States
Evaluating AGuIX® Nanoparticles in Combination With Stereotactic Radiation for Brain Metastases
- First Posted Date
- 2019-09-18
- Last Posted Date
- 2021-06-08
- Lead Sponsor
- Centre Leon Berard
- Target Recruit Count
- 1
- Registration Number
- NCT04094077
- Locations
- 🇫🇷
Centre Léon Bérard, Lyon, France
🇫🇷Centre Antoine Lacassagne, Nice, France
Radiotherapy of Multiple Brain Metastases Using AGuIX®
- Conditions
- Brain Metastases, AdultRadiotherapy
- Interventions
- Radiation: Whole Brain Radiation Therapy
- First Posted Date
- 2019-01-28
- Last Posted Date
- 2024-06-14
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 100
- Registration Number
- NCT03818386
- Locations
- 🇫🇷
Centre Hospitalier Annecy Genevois, Annecy, Rhones-Alpes, France
🇫🇷Centre Leon Berard Lyon, Lyon, Rhones Alpes, France
🇫🇷Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, Rhones-Alpes, France
Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles
- Conditions
- Brain Metastases
- Interventions
- Radiation: whole brain radiation therapy
- First Posted Date
- 2016-07-01
- Last Posted Date
- 2019-06-07
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 15
- Registration Number
- NCT02820454
- Locations
- 🇫🇷
University Hospital Grenoble, Grenoble, France
Drug Development Updates
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