Azithromycin

Generic Name: Azithromycin

Brand Names: Azasite, Zithromax, Zmax

Drug Type: Small Molecule

Chemical Formula: C_₃₈H_₇₂N_₂O_₁₂

CAS Number: 83905-01-5

Unique Ingredient Identifier: J2KLZ20U1M

Background: Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 .
...

Indication: Azithromycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria in order to prevent the development antimicrobial resistance and maintain the efficacy of azithromycin .
...

Associated Conditions: Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Acute bacterial exacerbation of COPD caused by Haemophilus Influenza Infections, Moraxella Catarrhalis Infection, Streptococcus Pneumoniae Infections, Bacterial Conjunctivitis, Bacterial Sinusitis, Cervicitis, Chancroid, Community Acquired Pneumonia (CAP), Genital Ulcer Disease (GUD), Pelvic Inflammatory Disease (PID), Pharyngitis, Streptococcal Pharyngitis, Tonsillitis bacterial, Tonsillitis streptococcal, Traveler's Diarrhea, Uncomplicated Skin and Skin Structure Infections, Urethritis

Associated Therapies: -

Clinical Trials

Trial II of Lung Protection With Azithromycin in the Preterm Infant

Phase 2

Completed

Conditions: Bronchopulmonary Dysplasia

Interventions: Drug: Placebo
Drug: Azithromycin

First Posted Date: 2006-04-27

Last Posted Date: 2018-06-27

Lead Sponsor: Hubert Ballard

Target Recruit Count: 220

Registration Number: NCT00319956

Locations: 🇺🇸
University of Kentucky Medical Center, Lexington, Kentucky, United States

Intrapulmonary Pharmacokinetics of Antibiotics

Phase 4

Terminated

Conditions: Healthy

First Posted Date: 2006-04-18

Last Posted Date: 2009-02-13

Lead Sponsor: University of Illinois at Chicago

Target Recruit Count: 35

Registration Number: NCT00315601

Locations: 🇺🇸
Pulmonary Associates PA, Phoenix, Arizona, United States

TELI COM - Telithromycin in Children With Otitis Media

Phase 3

Terminated

Conditions: Otitis Media, Suppurative
Otitis Media, Purulent

First Posted Date: 2006-04-17

Last Posted Date: 2009-04-03

Lead Sponsor: Sanofi

Target Recruit Count: 1500

Registration Number: NCT00315003

Locations: 🇵🇪
Sanofi-Aventis, Lima, Peru

Azithromycin Combination Therapy for Malaria

Phase 2

Completed

Conditions: Plasmodium Falciparum Malaria

First Posted Date: 2006-03-06

Last Posted Date: 2010-08-27

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 120

Registration Number: NCT00299208

Locations: 🇹🇭
Mahidol University Hospital for Tropical Diseases, Bangkok, Thailand

Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex

Phase 2

Conditions: Cystic Fibrosis

Interventions: Drug: Placebo
Drug: Azithromycin

First Posted Date: 2006-03-03

Last Posted Date: 2009-07-31

Lead Sponsor: Unity Health Toronto

Target Recruit Count: 45

Registration Number: NCT00298922

Locations: 🇨🇦
St. Michael's Hospital, Toronto, Ontario, Canada

Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women

Not Applicable

Completed

Conditions: Malaria

First Posted Date: 2006-02-06

Last Posted Date: 2006-02-06

Lead Sponsor: University of North Carolina

Target Recruit Count: 141

Registration Number: NCT00287300

Locations: 🇲🇼
Mpemba and Madziabango Health Centers, Blantyre, Malawi

Azithromycin in Control of Trachoma II

Phase 4

Withdrawn

Conditions: Trachoma

Interventions: Drug: Azithromycin

First Posted Date: 2006-02-02

Last Posted Date: 2012-04-16

Lead Sponsor: University of California, San Francisco

Registration Number: NCT00286026

Locations: 🇺🇸
University of California, San Francisco, San Francisco, California, United States

AZMATICS: AZithroMycin/Asthma Trial In Community Settings

Phase 3

Completed

Conditions: Asthma

Interventions: Drug: Placebo
Drug: Azithromycin

First Posted Date: 2005-12-19

Last Posted Date: 2019-09-06

Lead Sponsor: University of Wisconsin, Madison

Target Recruit Count: 97

Registration Number: NCT00266851

Locations: 🇺🇸
ANSR, Peoria, Illinois, United States
🇺🇸
RAP - Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸
University of Oklahoma Health Sciences Center (OUHSC) and Oklahoma Physicians Resource/Research Network (OKPRN), Oklahoma City, Oklahoma, United States

and more 2 locations

ASTHMA (AntibioticS To Help Manage Asthma) Pilot Study

Phase 3

Completed

Conditions: Asthma

First Posted Date: 2005-10-28

Last Posted Date: 2005-10-28

Lead Sponsor: Wisconsin Research Network

Target Recruit Count: 100

Registration Number: NCT00245908

Outpatient Registry Trial of Respiratory Tract Infections in Adults

Phase 4

Withdrawn

Conditions: Pneumonia, Bacterial
Bronchitis, Chronic

Interventions: Drug: azithromycin
Drug: Clarythromycin
Drug: telithromycin

First Posted Date: 2005-10-28

Last Posted Date: 2015-07-28

Lead Sponsor: CPL Associates

Registration Number: NCT00245453

Locations: 🇺🇸
Western Kentucky Pulmonary Clinic, Louisville, Kentucky, United States
🇺🇸
Northshore Research Associates, Slidell, Louisiana, United States

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy