Azithromycin

Generic Name
Azithromycin
Brand Names
Azasite, Zithromax, Zmax
Drug Type
Small Molecule
Chemical Formula
C38H72N2O12
CAS Number
83905-01-5
Unique Ingredient Identifier
J2KLZ20U1M
Background

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 .
...

Indication

Azithromycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria in order to prevent the development antimicrobial resistance and maintain the efficacy of azithromycin .
...

Associated Conditions
Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Acute bacterial exacerbation of COPD caused by Haemophilus Influenza Infections, Moraxella Catarrhalis Infection, Streptococcus Pneumoniae Infections, Bacterial Conjunctivitis, Bacterial Sinusitis, Cervicitis, Chancroid, Community Acquired Pneumonia (CAP), Genital Ulcer Disease (GUD), Pelvic Inflammatory Disease (PID), Pharyngitis, Streptococcal Pharyngitis, Tonsillitis bacterial, Tonsillitis streptococcal, Traveler's Diarrhea, Uncomplicated Skin and Skin Structure Infections, Urethritis
Associated Therapies
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Azithromycin in the Treatment of Cryptosporidiosis in Patients Who Have Not Had Success With Other Drugs

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Pfizer
Registration Number
NCT00002328
Locations
🇺🇸

Pfizer Central Research, Groton, Connecticut, United States

Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.

First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Anderson Clinical Research
Registration Number
NCT00002192
Locations
🇺🇸

Hampton Roads Med Specialists, Hampton, Virginia, United States

Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Pfizer
Registration Number
NCT00002082
Locations
🇺🇸

Univ of Tennessee, Memphis, Tennessee, United States

🇺🇸

Cornell Univ Med Ctr, New York, New York, United States

🇺🇸

Infectious Disease Med Group, Oakland, California, United States

and more 1 locations

A Randomized Study of Daily and Intermittent Prophylactic Regimens for the Prevention of Disseminated Mycobacterium Avium Complex (MAC) and Fungal Infections in HIV-Infected Patients

First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Pfizer
Target Recruit Count
720
Registration Number
NCT00002122
Locations
🇺🇸

Los Angeles County - USC Med Ctr, Los Angeles, California, United States

🇺🇸

UCSD Treatment Ctr / Dept of Medicine and Pediatrics, San Diego, California, United States

🇺🇸

Univ of Massachusetts Med Ctr, Worcester, Massachusetts, United States

and more 9 locations

The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients

First Posted Date
2001-08-31
Last Posted Date
2012-10-31
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
91
Registration Number
NCT00001023
Locations
🇺🇸

Univ of Maryland at Baltimore / Veterans Adm, Baltimore, Maryland, United States

🇺🇸

Denver Public Health Dept, Denver, Colorado, United States

🇺🇸

Med College of Virginia / School of Pharmacy, Richmond, Virginia, United States

and more 8 locations

Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy

First Posted Date
2001-08-31
Last Posted Date
2012-10-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
636
Registration Number
NCT00000883
Locations
🇺🇸

Univ of California / San Diego Treatment Ctr, San Diego, California, United States

🇺🇸

Cook County Hosp, Chicago, Illinois, United States

🇺🇸

Emory Univ, Atlanta, Georgia, United States

and more 48 locations

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.

First Posted Date
2001-08-31
Last Posted Date
2021-11-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
90
Registration Number
NCT00000641
Locations
🇺🇸

St. Louis ConnectCare, Infectious Diseases Clinic, Saint Louis, Missouri, United States

🇺🇸

Washington U CRS, Saint Louis, Missouri, United States

🇺🇸

NY Univ. HIV/AIDS CRS, New York, New York, United States

and more 13 locations

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
690
Registration Number
NCT00000811
Locations
🇺🇸

Saint Christopher's Hosp for Children, Philadelphia, Pennsylvania, United States

🇵🇷

San Juan City Hosp, San Juan, Puerto Rico

🇺🇸

Texas Children's Hosp / Baylor Univ, Houston, Texas, United States

and more 72 locations

Treatment of Chronic Cryptosporidiosis in AIDS Patients

Not Applicable
Terminated
Conditions
First Posted Date
2001-08-31
Last Posted Date
2016-12-14
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
16
Registration Number
NCT00001128
Locations
🇺🇸

Pablo C. Okhuysen, Houston, Texas, United States

A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-08-26
Lead Sponsor
Pfizer
Target Recruit Count
45
Registration Number
NCT00000966
Locations
🇺🇸

Los Angeles County - USC Med Ctr, Los Angeles, California, United States

🇺🇸

Univ of Massachusetts Med Ctr, Worcester, Massachusetts, United States

🇺🇸

Univ of Miami School of Medicine, Miami, Florida, United States

and more 8 locations
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