Papaverine
- Generic Name
- Papaverine
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21NO4
- CAS Number
- 58-74-2
- Unique Ingredient Identifier
- DAA13NKG2Q
Overview
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Background
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Indication
For the treatment of impotence and vasospasms.
Associated Conditions
- Vascular spasm
- Visceral spasms
Clinical Trials
FDA Approved Products
Singapore Approved Products
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