Metronidazole

Generic Name
Metronidazole
Brand Names
Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole
Drug Type
Small Molecule
Chemical Formula
C6H9N3O3
CAS Number
443-48-1
Unique Ingredient Identifier
140QMO216E
Background

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication

Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions
Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis
Associated Therapies
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Helicobacter Pylori Rescue Treatment in Patients Allergic to Penicillin

First Posted Date
2021-11-26
Last Posted Date
2021-11-30
Lead Sponsor
Shandong University
Target Recruit Count
170
Registration Number
NCT05135182
Locations
🇨🇳

Qilu hosipital, Jinan, Shandong, China

Helicobacter Pylori First-line Treatment Containing Tetracycline in Patients Allergic to Penicillin

First Posted Date
2021-11-22
Last Posted Date
2021-11-24
Lead Sponsor
Shandong University
Target Recruit Count
106
Registration Number
NCT05129176
Locations
🇨🇳

Qilu hospital, Jinan, Shandong, China

Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection

First Posted Date
2021-10-29
Last Posted Date
2021-10-29
Lead Sponsor
Hospital da Senhora da Oliveira
Target Recruit Count
100
Registration Number
NCT05100446
Locations
🇵🇹

Vítor Bruno Macedo da Silva, Guimarães, Portugal

Helicobacter Pylori Eradication and Follow-up

First Posted Date
2021-09-30
Last Posted Date
2021-09-30
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
4447
Registration Number
NCT05061732
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication

First Posted Date
2021-09-20
Last Posted Date
2023-07-19
Lead Sponsor
Shandong University
Target Recruit Count
1300
Registration Number
NCT05049902
Locations
🇨🇳

Maternity and Child Care Health Center of Dezhou, Dezhou, Shandong, China

🇨🇳

Heze Municipal 3rd people's hospital, Heze, Shandong, China

🇨🇳

Qilu hosipital, Jinan, Shandong, China

and more 3 locations

Antibiotic Combination for H. Pylori Eradication in Penicillin-allergic Patients

First Posted Date
2021-08-26
Last Posted Date
2021-09-14
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
504
Registration Number
NCT05023577
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

Tetracycline Versus Doxycycline for HP Rescue Therapy

First Posted Date
2021-08-24
Last Posted Date
2021-08-26
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
242
Registration Number
NCT05018923
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

PPI-amoxicillin for H. Pylori Treatment

First Posted Date
2021-08-20
Last Posted Date
2021-08-23
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
732
Registration Number
NCT05014685
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

Refined Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis (UC)

First Posted Date
2021-07-20
Last Posted Date
2024-02-26
Lead Sponsor
Ari M Grinspan
Target Recruit Count
4
Registration Number
NCT04968951
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Study to Assess Efficacy and Safety of PF-06947386 in Japanese Adult Patients With Complicated Intra-abdominal Infection

First Posted Date
2021-06-15
Last Posted Date
2024-03-13
Lead Sponsor
Pfizer
Target Recruit Count
60
Registration Number
NCT04927312
Locations
🇯🇵

Saiseikai Maebashi Hospital, Maebashi, Gunma, Japan

🇯🇵

Yamagata City Hospital Saiseikan, Yamagata, Japan

🇯🇵

National Hospital Organization Osaka Minami Medical Center, Kawachinagano, Osaka, Japan

and more 25 locations
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