Metronidazole

Generic Name: Metronidazole

Brand Names: Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole

Drug Type: Small Molecule

Chemical Formula: C_₆H_₉N_₃O_₃

CAS Number: 443-48-1

Unique Ingredient Identifier: 140QMO216E

Background: Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication: Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions: Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis

Associated Therapies: -

Clinical Trials

Tailored Therapy for Helicobacter Pylori Treatment in Patients With Penicillin Allergy

Phase 4

Completed

Conditions: Helicobacter Pylori Infection

Interventions: Drug: Esomeprazole
Drug: Bismuth Potassium Citrate
Drug: Clarithromycin
Drug: Metronidazole
Drug: Levofloxacin
Drug: Tetracycline

First Posted Date: 2018-10-17

Last Posted Date: 2019-12-10

Lead Sponsor: Shanghai Jiao Tong University School of Medicine

Target Recruit Count: 112

Registration Number: NCT03708848

Locations: 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China

Effectiveness of Saccharomyces Boulardii for Gastrointestinal Bacterial-overgrowth in Systemic Sclerosis

Phase 4

Completed

Conditions: Systemic Sclerosis
Small Intestinal Bacterial Overgrowth

Interventions: Drug: Saccharomyces Boulardii Oral Tablet
Drug: Metronidazole

First Posted Date: 2018-10-02

Last Posted Date: 2019-07-30

Lead Sponsor: Coordinación de Investigación en Salud, Mexico

Target Recruit Count: 39

Registration Number: NCT03692299

Locations: 🇲🇽
Maria del Pilar Cruz Dominguez, Mexico, Mexico City, Mexico

Bowel Preparation in Elective Pediatric Colorectal Surgery

Not Applicable

Conditions: Hirschsprung Disease - Pull Through
Necrotizing Enterocolitis
Inflammatory Bowel Diseases
Bowel Obstruction
Elective Surgery
Colostomy
Meconium Ileus

Interventions: Drug: Senna
Drug: Sodium Picosulfate, Magnesium Oxide and Citric Acid
Other: Nil per os
Drug: Metronidazole Oral
Drug: Neomycin
Drug: Cefazolin
Drug: Metronidazole
Other: Clear fluids the day before surgery

First Posted Date: 2018-07-20

Last Posted Date: 2021-12-09

Lead Sponsor: McMaster University

Target Recruit Count: 81

Registration Number: NCT03593252

Responses to Rabies Vaccine in Adults With or Without Antibiotics

Phase 4

Completed

Conditions: Rabies Human

Interventions: Biological: Rabies Vaccine
Drug: Metronidazole
Drug: Vancomycin
Drug: Neomycin Sulfate

First Posted Date: 2018-06-14

Last Posted Date: 2023-06-08

Lead Sponsor: Emory University

Target Recruit Count: 37

Registration Number: NCT03557008

Locations: 🇺🇸
Winship Cancer Institute of Emory University, Atlanta, Georgia, United States
🇺🇸
The Hope Clinic of the Emory Vaccine Center, Decatur, Georgia, United States