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Ensulizole is an ingredient used in sunscreens to absorb UVB radiation.
Ensulizole is an ingredient used in sunscreens to absorb UVB radiation.
Ensulizole strongly absorbs UV-B wavelengths. It offers protection against UV-B-induced cyclobutane pyrimidine dimers . Based on the findings in vitro and in cellulo, ensulizole induces damage on the DNA, causes DNA strand breaks and photosensitizes the formation of oxidized guanines via type I and II photosensitization mechanisms following UV-A or UV-B irradiation . Ensulizole is capable of generating reactive oxygen species, including singlet oxygen upon photoexcitation .
Indicated to be used as an UV-B-absorbing molecule in sunscreen formulations.
