Ensulizole
- Generic Name
- Ensulizole
- Brand Names
- Eucerin
- Drug Type
- Small Molecule
- Chemical Formula
- C13H10N2O3S
- CAS Number
- 27503-81-7
- Unique Ingredient Identifier
- 9YQ9DI1W42
Overview
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less oily . It was demonstrated by studies that ensulizole treatment provided protection against cyclobutane pyrimidine dimers and photosensitized the formation of oxidized guanine bases after UV-A or UV-B exposure . According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in commercial sunscreen products .
Background
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less oily . It was demonstrated by studies that ensulizole treatment provided protection against cyclobutane pyrimidine dimers and photosensitized the formation of oxidized guanine bases after UV-A or UV-B exposure . According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in commercial sunscreen products .
Indication
Indicated to be used as an UV-B-absorbing molecule in sunscreen formulations.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
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No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
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No FDA products found
No FDA products found for this drug
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
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No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
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No HSA products found
No HSA products found for this drug
NMPA Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
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No NMPA products found
No NMPA products found for this drug
PPB Approved Products
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
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No PPB products found
No PPB products found for this drug
TGA Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|---|---|---|---|---|
271593 | Active | 2016/02/29 | phenylbenzimidazole sulfonic acid | ||
226086 | Active | 2014/07/22 | phenylbenzimidazole sulfonic acid | ||
371951 | Active | 2021/08/02 | phenylbenzimidazole sulfonic acid | ||
411213 | Active | 2023/06/26 | phenylbenzimidazole sulfonic acid | ||
481365 | Active | 2025/03/03 | phenylbenzimidazole sulfonic acid | ||
343242 | Active | 2020/09/10 | phenylbenzimidazole sulfonic acid | ||
401273 | Active | 2022/12/19 | phenylbenzimidazole sulfonic acid | ||
433392 | Active | 2024/01/10 | phenylbenzimidazole sulfonic acid | ||
432870 | Active | 2024/01/08 | phenylbenzimidazole sulfonic acid | ||
477153 | Active | 2025/01/30 | phenylbenzimidazole sulfonic acid |