Isoniazid
- Generic Name
- Isoniazid
- Brand Names
- Isonarif, Isotamine, Isotamine B, Rifamate, Rifater
- Drug Type
- Small Molecule
- Chemical Formula
- C6H7N3O
- CAS Number
- 54-85-3
- Unique Ingredient Identifier
- V83O1VOZ8L
- Background
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
- Indication
Isoniazid is used for the treatment of all forms of tuberculosis in which organisms are susceptible. It is also used in combination with rifampin and pyrazinamide.
- Associated Conditions
- Active Tuberculosis, Mycobacterium kansasii infection, Late phase Tuberculosis
- Associated Therapies
- -
Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment
- Conditions
- Interventions
- First Posted Date
- 2022-07-12
- Last Posted Date
- 2022-07-12
- Lead Sponsor
- First Affiliated Hospital of Zhejiang University
- Target Recruit Count
- 620
- Registration Number
- NCT05454345
Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis
- First Posted Date
- 2022-05-20
- Last Posted Date
- 2024-08-21
- Target Recruit Count
- 330
- Registration Number
- NCT05383742
- Locations
- 🇲🇼
Malawi CRS, Lilongwe, Malawi
🇧🇷Hospital Nossa Senhora da Conceicao CRS (12201), Porto Alegre, Brazil
🇧🇷Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS (12101), Rio De Janeiro, Brazil
The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney Transplantation
- Conditions
- Interventions
- First Posted Date
- 2022-02-22
- Last Posted Date
- 2022-04-04
- Lead Sponsor
- West China Hospital
- Target Recruit Count
- 303
- Registration Number
- NCT05249699
Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV
- Conditions
- Interventions
- First Posted Date
- 2021-11-16
- Last Posted Date
- 2024-03-18
- Lead Sponsor
- The Aurum Institute NPC
- Target Recruit Count
- 252
- Registration Number
- NCT05122026
- Locations
- 🇿🇦
The Aurum Institute: Tembisa Clinical Research Centre, Tembisa, Gauteng, South Africa
🇿🇦Peri Natal HIV Research Unit - Klerksdorp Tshepong Hospital, Klerksdorp, North-West, South Africa
🇿🇦FAMily Centre for Research with Ubuntu (FAMCRU), Cape Town, South Africa
Four Months Moxifloxacin Containing Daily Regimen Study Among New Pulmonary Tuberculosis Patients
- Conditions
- Interventions
- First Posted Date
- 2021-09-16
- Last Posted Date
- 2024-01-05
- Lead Sponsor
- Tuberculosis Research Centre, India
- Target Recruit Count
- 550
- Registration Number
- NCT05047055
- Locations
- 🇮🇳
National Institute for Research in Tuberculosis, Chennai, Tamilnadu, India
Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)
- Conditions
- Interventions
- First Posted Date
- 2021-06-18
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- University of Massachusetts, Worcester
- Target Recruit Count
- 112
- Registration Number
- NCT04930744
- Locations
- 🇿🇦
Isango Lethemba TB Research Unit, Port Elizabeth, South Africa
🇿🇦Tembisa Clinical Research Centre-The Aurum Institute, Johannesburg, Gauteng, South Africa
Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device Insertion
- Conditions
- Interventions
- First Posted Date
- 2020-08-10
- Last Posted Date
- 2020-08-18
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT04505943
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Rosuvastatin Evaluation as a Tuberculosis Treatment Adjunct
- Conditions
- Interventions
- First Posted Date
- 2020-08-07
- Last Posted Date
- 2020-08-07
- Lead Sponsor
- National University Hospital, Singapore
- Target Recruit Count
- 154
- Registration Number
- NCT04504851
- Locations
- 🇺🇬
Joint Clinical Research Centre, Kampala, Uganda
🇻🇳Vietnam Military Medical University, Hanoi, Vietnam
🇵🇭Tropical Disease Foundation, Makati City, Philippines
Vaginal Dinoprostone Versus Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy
- First Posted Date
- 2020-08-05
- Last Posted Date
- 2021-09-29
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT04500496
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
- Conditions
- Interventions
- First Posted Date
- 2020-08-05
- Last Posted Date
- 2020-08-05
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT04500002
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.