DeepMed Research

Nitrate

Generic Name: Nitrate

Drug Type: Small Molecule

Chemical Formula: NO_₃

CAS Number: 14797-55-8

Unique Ingredient Identifier: T93E9Y2844

Clinical Trials

Improving Mobility After Revascularization in Peripheral Artery Disease

Phase 3

Not yet recruiting

Conditions: Peripheral Artery Disease
Intermittent Claudication
Peripheral Vascular Disease
Mobility Limitation
Revascularization

Interventions: Behavioral: Home Based Exercise
Drug: Nitrate Rich Beetroot Juice
Drug: Placebo Beetroot Juice Without Nitrate
Behavioral: Attention Control

First Posted Date: 2024-11-13

Last Posted Date: 2024-11-13

Lead Sponsor: Northwestern University

Target Recruit Count: 386

Registration Number: NCT06686121

Locations: 🇺🇸
University of Arizona, Tucson, Arizona, United States
🇺🇸
Rancho Research Institute, Downey, California, United States
🇺🇸
Emory University School of Medicine, Atlanta, Georgia, United States

and more 5 locations

Bronchoscopic Lung Volume Reduction in Management of Localized Emphysema

Not Applicable

Recruiting

Conditions: Bronchoscopic Lung Volume Reduction

Interventions: Drug: Nano-silver nitrate
Drug: Silver Nitrate
Device: Bronchoscopic lung volume reduction

First Posted Date: 2024-10-07

Last Posted Date: 2024-10-07

Lead Sponsor: Mansoura University Hospital

Target Recruit Count: 30

Registration Number: NCT06629558

Locations: 🇪🇬
Mohamed AbdElmoniem, Mansoura, Egypt

Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial).

Phase 4

Active, not recruiting

Conditions: Myocardial Infarction With Non-Obstructive Coronary Arteries

Interventions: Procedure: Coronary angiography
Diagnostic Test: OCT imaging
Diagnostic Test: Acetylcholine provocative test
Diagnostic Test: TT-Echocardiography
Diagnostic Test: TE/contrast echocardiography
Diagnostic Test: Cardiac magnetic resonance
Diagnostic Test: Circulating biomarkers
Drug: Antiplatelet Drug
Drug: Statin
Drug: Beta blocker
Drug: ACEi/ARB
Drug: CCB
Drug: Nitrates
Drug: Anticoagulant

First Posted Date: 2021-11-17

Last Posted Date: 2024-07-26

Lead Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Target Recruit Count: 120

Registration Number: NCT05122780

Locations: 🇮🇹
Centro Cardiologico Monzino, Milan, Italy
🇮🇹
Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
🇮🇹
IRCCS Policlinico San Donato, San Donato Milanese, Italy

Study on the Effectiveness and Safety of Nitrone for Injection in Patients With Acute Ischemic Stroke

Not Applicable

Conditions: Acute Ischemic Stroke

Interventions: Drug: Nitrate ketone oxazine

First Posted Date: 2021-07-06

Last Posted Date: 2021-07-06

Lead Sponsor: Peking University Third Hospital

Target Recruit Count: 200

Registration Number: NCT04951440

Locations: 🇨🇳
: Beijing Dan's self technology co., LTD., Beijing, China
🇨🇳
Tiantan Hospital, Capital Medical University, Beijing, China

Effect of Ultimaster Stents Treated to the Most Dilated Coronary Vessels

Not Applicable

Conditions: Vasodilation
Coronary Artery Disease

Interventions: Drug: Nitrate

First Posted Date: 2021-06-18

Last Posted Date: 2021-06-18

Lead Sponsor: Inha University Hospital

Target Recruit Count: 400

Registration Number: NCT04931784

Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension

Phase 1

Withdrawn

Conditions: Pulmonary Hypertension
Pulmonary Heart Disease and Diseases of Pulmonary Circulation
Heart Failure With Normal Ejection Fraction

Interventions: Drug: Nitrates
Drug: Chlorhexidine Gluconate Mouthwash
Drug: Placebo Mouthwash

First Posted Date: 2018-12-26

Last Posted Date: 2022-07-07

Lead Sponsor: Gladwin, Mark, MD

Registration Number: NCT03787082

Locations: 🇺🇸
Cathy Kessinger, Pittsburgh, Pennsylvania, United States

Postmenopausal Women and Their Endothelium

Phase 2

Completed

Conditions: Postmenopausal Women

Interventions: Drug: nitrate depleted beetroot juice
Drug: nitrate rich beetroot juice

First Posted Date: 2018-08-23

Last Posted Date: 2023-02-27

Lead Sponsor: Penn State University

Target Recruit Count: 37

Registration Number: NCT03644472

Locations: 🇺🇸
Penn State University, University Park, Pennsylvania, United States

Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial

Phase 2

Terminated

Conditions: Heart Failure
Heart Failure Acute
Acute Cardiac Failure
Acute Cardiac Pulmonary Edema

Interventions: Drug: Loop Diuretics
Drug: Nitrates

First Posted Date: 2017-08-23

Last Posted Date: 2024-08-20

Lead Sponsor: Indiana University

Target Recruit Count: 52

Registration Number: NCT03259165

Locations: 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States
🇺🇸
Eskenazi Health, Indianapolis, Indiana, United States
🇺🇸
IU Health Methodist Hospital, Indianapolis, Indiana, United States

A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction

Phase 1

Completed

Conditions: Pulmonary; Hypertension
Heart Failure
Preserved Ejection Fraction

Interventions: Drug: 15N Nitrate
Drug: 14N Nitrate

First Posted Date: 2016-12-02

Last Posted Date: 2022-03-22

Lead Sponsor: Gladwin, Mark, MD

Target Recruit Count: 77

Registration Number: NCT02980068

Locations: 🇺🇸
Nydia Chien, Pittsburgh, Pennsylvania, United States
🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States

Nitrate Patch Use as Treatment of Knee AVN

Not Applicable

Terminated

Conditions: Necrosis, Avascular, of Bone

Interventions: Drug: nitrate patch
Drug: placebo patch
Device: MRI scan

First Posted Date: 2013-11-08

Last Posted Date: 2024-04-02

Lead Sponsor: Sheba Medical Center

Target Recruit Count: 30

Registration Number: NCT01979666

Locations: 🇮🇱
Sheba Medical Center, Ramat Gan, Israel

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2025. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy