Goserelin

Generic Name
Goserelin
Brand Names
Zoladex
Drug Type
Small Molecule
Chemical Formula
C59H84N18O14
CAS Number
65807-02-5
Unique Ingredient Identifier
0F65R8P09N
Background

Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state. When the medication is stopped, hormone levels return...

Indication

Goserelin is indicated for:

Associated Conditions
Abnormal Uterine Bleeding, Advanced Breast Cancer, Endometriosis, Advanced carcinoma of the prostate, Stage T2b carcinoma of the prostate, Stage T4 carcinoma of the prostate
Associated Therapies
Palliative Treatment

Evaluating the Role of the Addition of Ovarian Function Suppression (OFS) to Tamoxifen in Young Women

Phase 3
Conditions
Interventions
First Posted Date
2009-06-03
Last Posted Date
2009-06-16
Lead Sponsor
Korean Breast Cancer Study Group
Target Recruit Count
1234
Registration Number
NCT00912548
Locations
🇰🇷

Department of Surgery, Korea Cancer Center Hospital, Seoul, Korea, Republic of

Investigation of the Effect of Degarelix in Terms of Prostate Volume Reduction in Prostate Cancer Patients

First Posted Date
2009-04-20
Last Posted Date
2013-11-13
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
182
Registration Number
NCT00884273
Locations
🇮🇹

Azienda Ospedaliero Universitaria Ospedali riuniti, Ancona, Italy

🇧🇪

Institut Jules Bordet, Bruxelles, Belgium

🇫🇮

KYS/kirurgian klin (Kuopio), Kuopio, Finland

and more 43 locations

Effect of Goserelin (Zoladex®) in Spinal and Bulbar Muscular Atrophy

First Posted Date
2009-02-26
Last Posted Date
2015-05-21
Lead Sponsor
Ramathibodi Hospital
Target Recruit Count
10
Registration Number
NCT00851461
Locations
🇹🇭

Medical Genetics and Molecular Medicine Unit,, Department of Medicine, Ramathibodi Hospital, Bangkok, Thailand

Neoadjuvant Study Investigating Degarelix in Patients Suffering From Prostate Cancer

First Posted Date
2009-02-02
Last Posted Date
2012-10-04
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
246
Registration Number
NCT00833248
Locations
🇬🇧

Kent Oncology Centre Maidstone Hospital, Maidstone, Kent, United Kingdom

🇫🇷

Clinique du Parc, Toulouse, France

🇫🇷

Centre de Lutte Contre le Cancer Nantes-Atlantique Centre René Gauducheau, Saint Herblain Cedex, France

and more 63 locations

Symptomatic Study Investigating Degarelix in Patients Suffering From Prostate Cancer

First Posted Date
2009-01-28
Last Posted Date
2013-11-11
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
42
Registration Number
NCT00831233
Locations
🇪🇸

Fundación Puigvert, Barcelona, Spain

🇪🇸

Fundacion Hospital Alcorcón, Alcorcon, Spain

🇪🇸

Hospital de Basurto, Bilbao (Bizkaia), Spain

and more 29 locations

Zoladex Plus Tamoxifen in Breast Cancer

First Posted Date
2009-01-22
Last Posted Date
2011-08-08
Lead Sponsor
Zhejiang Cancer Hospital
Target Recruit Count
100
Registration Number
NCT00827307
Locations
🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

Study of Effectiveness of IMC-A12 Antibody Combined With Hormone Therapy Prior to Surgery to Treat Prostate Cancer

First Posted Date
2008-10-09
Last Posted Date
2017-03-29
Lead Sponsor
University of Washington
Target Recruit Count
29
Registration Number
NCT00769795
Locations
🇺🇸

Seattle Cancer Care Alliance, Seattle, Washington, United States

🇺🇸

Virginia Mason Medical Center, Seattle, Washington, United States

🇺🇸

University of Washington Medical Center, Seattle, Washington, United States

Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer

First Posted Date
2008-04-02
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
48
Registration Number
NCT00651326
Locations
🇨🇦

McGill University - Dept. Oncology, Montreal, Canada

🇨🇦

Tom Baker Cancer Centre, Calgary, Canada

🇨🇦

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Canada

and more 10 locations

Sunitinib Malate, Hormone Ablation and Radiation Therapy in Patients With Prostate Cancer

First Posted Date
2008-03-07
Last Posted Date
2015-01-29
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
19
Registration Number
NCT00631527
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

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