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Pantothenic acid

Generic Name
Pantothenic acid
Brand Names
Concept Ob, Irospan 24/6 Kit, Pregvit, Tandem Plus
Drug Type
Small Molecule
Chemical Formula
C9H17NO5
CAS Number
79-83-4
Unique Ingredient Identifier
19F5HK2737

Overview

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate. Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado, and yogurt. Pantothenic acid is an ingredient in some hair and skin care products. Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer.

Background

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate. Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado, and yogurt. Pantothenic acid is an ingredient in some hair and skin care products. Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer.

Indication

Studied for the treatment of many uses such as treatment of testicular torsion, diabetic ulceration, wound healing, acne, obesity, diabetic peripheral polyneuropathy. It has also been investigated for its hypolipidemic effects and as cholesterol lowering agent.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2023/01/27
Not Applicable
Recruiting

FDA Approved Products

Product Name
Manufacturer
Route
Strength
Approved
NDC Code
Se-Natal 19 Chewable
Seton Pharmaceuticals
ORAL
7 mg in 1 1
2019/01/07
13925-117
Dialyvite 5000
Hillestad Pharmaceuticals USA
ORAL
10 mg in 1 1
2019/10/24
10542-011
Livita Adults
PureTek Corporation
ORAL
5 mg in 1 mL
2023/12/18
59088-659
Vita-Rx Diabetic Vitamin
Pure Source, LLC
ORAL
10 mg in 1 1
2023/11/22
65121-301
Strovite One Caplets
Exeltis USA, Inc.
ORAL
7.5 mg in 1 1
2023/01/02
0642-0207
MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement
MARTIN EKWEALOR PHARMACEUTICALS, INC.
ORAL
5 mg in 1 1
2013/12/13
58607-186
BACMIN
Marnel Pharmaceuticals, Inc.
ORAL
25 mg in 1 1
2014/05/02
0682-3001
PNV-Select
Acella Pharmaceuticals, LLC
ORAL
6 mg in 1 1
2020/01/17
42192-320
Se-Natal 19
Seton Pharmaceuticals
ORAL
7 mg in 1 1
2019/01/07
13925-116
Dialyvite
Carilion Materials Management
ORAL
10 mg in 1 1
2015/12/29
68151-4402

EMA Approved Products

Medicine Name
EMA Number
Auth. Holder
Country
Drug Type
Status
Issued
Opinion
Revision

No EMA products found

No EMA products found for this drug

Singapore Approved Products

Product Name
Manufacturer
Dosage Form
Strength
Approved
Approval No.
Online

No Singapore products found

No Singapore products found for this drug

China Approved Products

Product Name
Approval No.
Manufacturer
Dosage Form
Trade Name
Strength
Type
Status
Date
Import
Calcium Pantothenate Tablets
国药准字H11020031
华润紫竹药业有限公司
片剂
N/A
10mg
Chemical Drug
Approved
2020/11/24
Domestic
Calcium Pantothenate Tablets
国药准字H41021211
洛阳伊龙药业有限公司
片剂
N/A
10毫克
Chemical Drug
Approved
2020/06/05
Domestic
Calcium Pantothenate Tablets
国药准字H44023273
三才石岐制药股份有限公司
片剂
N/A
10mg
Chemical Drug
Approved
2020/09/07
Domestic
Calcium Pantothenate Tablets
国药准字H44021109
特一药业集团股份有限公司
片剂
N/A
10mg
Chemical Drug
Approved
2015/08/13
Domestic
Calcium Pantothenate Tablets
国药准字H44020020
广州白云山光华制药股份有限公司
片剂
N/A
10mg
Chemical Drug
Approved
2020/05/15
Domestic
Calcium Pantothenate Tablets
国药准字H12020218
天津市力生制药厂
片剂
N/A
5mg
Chemical Drug
Approved
2020/08/13
Domestic

Australia Approved Products

Product Name
ARTG ID
Sponsor
Status
Reg. Date
Ingredient
Energy Multi
453128
Australian Pharmaceutical Industries Pty Ltd
Active
2024/06/21
calcium pantothenate
Cellula-T oral powder jar
43995
Hong Sp & Hs
Active
1993/04/13
calcium pantothenate
BLACKMORES SUPERKIDS MULTI CHEWABLES
289492
Blackmores Ltd
Active
2017/05/30
calcium pantothenate
Super B Complex tablets
126510
Sphere Healthcare Pty Ltd
Active
2006/03/28
calcium pantothenate
BLACKMORES B+C TABLETS
215811
Blackmores Ltd
Active
2013/10/09
calcium pantothenate
MaxN-Fuze Multivitamins
288444
Max Health & Living Australia Pty Ltd
Active
2017/05/01
calcium pantothenate
Wealthy Health Bio-Maxi B Excellent Stress Relief Formula with Herbs
139048
Universal Pharmaceuticals Pty Ltd
Active
2007/05/21
calcium pantothenate
Caruso's Hair Food
130857
Caruso's Natural Health Pty Ltd
Active
2006/08/30
calcium pantothenate
Berocca Performance Original effervescent tablets
193893
Bayer Australia Ltd
Active
2012/01/17
calcium pantothenate
Kids Multi
329564
Factors Group Australia Pty Ltd
Active
2020/02/06
calcium pantothenate
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