Sotalol
- Generic Name
- Sotalol
- Brand Names
- Betapace, Sorine, Sotylize
- Drug Type
- Small Molecule
- Chemical Formula
- C12H20N2O3S
- CAS Number
- 3930-20-9
- Unique Ingredient Identifier
- A6D97U294I
- Background
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening ventricular arrhythmias and maintaining normal ...
- Indication
Sotalol is indicated to treat life threatening ventricular arrhytmias and maintain normal sinus rhythm in patients with atrial fibrillation or flutter. There are also oral solutions and intravenous injections indicated for patients requiring sotalol, but for whom a tablet would not be appropriate.
- Associated Conditions
- Sinus Rhythm, Life-threatening ventricular arrhythmias
- Associated Therapies
- -
Efficacy and Safety Evaluation of Azimilide or Sotalol vs Placebo for Treatment of Patients With Atrial Fibrillation.
- Conditions
- Interventions
- First Posted Date
- 2002-05-06
- Last Posted Date
- 2011-10-03
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 658
- Registration Number
- NCT00035451
- Locations
- 🇫🇷
Cardiologie A CHU Rangueil, Toulouse, France
🇧🇪Clinique Generale Saint Jean Service de cardiologie, Brussels, Belgium
🇫🇷CHR Besancon Service de cardiologie, Besancon, France
Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm
- Conditions
- Interventions
- First Posted Date
- 2001-01-01
- Last Posted Date
- 2011-06-15
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 706
- Registration Number
- NCT00007605
- Locations
- 🇺🇸
VA Medical Center, Augusta, Augusta, Georgia, United States
🇺🇸VA North Texas Health Care System, Dallas, Dallas, Texas, United States
🇺🇸VA Medical Center, Minneapolis, Minneapolis, Minnesota, United States
Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)
- Conditions
Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)
- Conditions
- First Posted Date
- 1999-10-28
- Last Posted Date
- 2013-07-29
- Lead Sponsor
- University of Washington
- Registration Number
- NCT00000464
Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)
- First Posted Date
- 1999-10-28
- Last Posted Date
- 2016-01-21
- Lead Sponsor
- University of Utah
- Registration Number
- NCT00000518
Antiarrhythmics Versus Implantable Defibrillators (AVID)
Drug Development Updates
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