MedPath

Fobrepodacin

Generic Name
Fobrepodacin
Drug Type
Small Molecule
Chemical Formula
C21H26FN6O6P
CAS Number
1384984-31-9
Unique Ingredient Identifier
1NL76YUU6E

A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2023-08-01
Last Posted Date
2024-03-04
Lead Sponsor
Spero Therapeutics
Target Recruit Count
39
Registration Number
NCT05966688
Locations
🇺🇸

Medpace Clinical Pharmacology Unit, Cincinnati, Ohio, United States

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2023-07-21
Last Posted Date
2024-03-07
Lead Sponsor
Spero Therapeutics
Target Recruit Count
33
Registration Number
NCT05955586
Locations
🇺🇸

Pulmonary Associates, Phoenix, Arizona, United States

Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Phase 2
Terminated
Conditions
Mycobacterium Avium Complex
Non-tuberculous Mycobacterium Pulmonary Disease
Interventions
Drug: Placebo
Drug: Open-label Standard of Care
First Posted Date
2020-09-17
Last Posted Date
2022-02-28
Lead Sponsor
Spero Therapeutics
Target Recruit Count
2
Registration Number
NCT04553406
Locations
🇺🇸

Medical Facility, Pittsburgh, Pennsylvania, United States

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