Mometasone

Generic Name
Mometasone
Brand Names
Asmanex, Dulera, Elocom, Elocon, Nasonex, Ryaltris, Sinuva, Zenhale
Drug Type
Small Molecule
Chemical Formula
C27H30Cl2O6
CAS Number
83919-23-7
Unique Ingredient Identifier
04201GDN4R
Background

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its ...

Indication

Inhaled mometasone furoate is indicated for prophylaxis of asthma in patients ≥4 years. Applied topically as an ointment, mometasone furoate is indicated for symptomatic treatment of dermatitis and pruritis in patients ≥2 years.
...

Associated Conditions
Asthma, Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), Dermatitis, Dermatitis, Eczematous caused by superficial Fungal skin infection, Moderate to Severe Plaque Psoriasis, Pruritus, Psoriasis, Psoriasis, Moderate to Severe, Seasonal Allergic Rhinitis, Seasonal Allergies, Skin Diseases, Eczematous, Skin Infections, Moderate, severe Seasonal Allergic Rhinitis, Ocular effects
Associated Therapies
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A Clinical Trial About Treatment of Mild to Moderate Persistent Alergic Rhinnitis With Test or Reference Mometasone (PUMA)

First Posted Date
2011-06-14
Last Posted Date
2017-09-18
Lead Sponsor
Eurofarma Laboratorios S.A.
Target Recruit Count
364
Registration Number
NCT01372865
Locations
🇧🇷

IMA Brasil - Instituto de Pesquisa Clínica e Medicina Avançada, Sao Paulo, Brazil

Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury

Phase 1
Conditions
Interventions
First Posted Date
2011-05-13
Last Posted Date
2015-10-23
Lead Sponsor
James J. Peters Veterans Affairs Medical Center
Target Recruit Count
50
Registration Number
NCT01353599
Locations
🇺🇸

Kessler Institute for Rehabilitation, West Orange, New Jersey, United States

🇺🇸

James J. Peters VA Medical Center, Bronx, New York, United States

Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo

First Posted Date
2011-04-12
Last Posted Date
2012-10-10
Lead Sponsor
Mahidol University
Target Recruit Count
30
Registration Number
NCT01333410
Locations
🇹🇭

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand

Effectiveness of Association Mometasone Furoate 0.1% and Salicylic Acid 5% Compared With Mometasone Furoate

First Posted Date
2010-10-26
Last Posted Date
2022-11-03
Lead Sponsor
Azidus Brasil
Target Recruit Count
40
Registration Number
NCT01228656

A Study of Long-term Administration of Mometasone Furoate Nasal Spray in Pediatric Subjects With Perennial Allergic Rhinitis (Study P06333AM1)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2010-07-19
Last Posted Date
2024-05-24
Lead Sponsor
Organon and Co
Target Recruit Count
80
Registration Number
NCT01165424

Nasonex® Nasal Suspension 50 μg Long-term Designated Drug Use Investigation (Study P05876)

Completed
Conditions
Interventions
First Posted Date
2009-05-18
Last Posted Date
2022-02-16
Lead Sponsor
Organon and Co
Target Recruit Count
3806
Registration Number
NCT00903721

Assessment of Intranasal Steroids in Allergic Rhinitis When Used Alone or in Combination With an Oral Antihistamine (Study P03270)

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-02-03
Last Posted Date
2024-08-15
Lead Sponsor
Organon and Co
Target Recruit Count
72
Registration Number
NCT00834119

A Study to Compare the Efficacy of QAV680 Against Placebo in Treating Seasonal Allergic Rhinitis in an Environmental Exposure Chamber

First Posted Date
2008-11-04
Last Posted Date
2016-11-18
Lead Sponsor
Novartis
Target Recruit Count
44
Registration Number
NCT00784732
Locations
🇨🇦

Novartis Investigator Site, Toronto, Canada

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