Mometasone

Generic Name
Mometasone
Brand Names
Asmanex, Dulera, Elocom, Elocon, Nasonex, Ryaltris, Sinuva, Zenhale
Drug Type
Small Molecule
Chemical Formula
C27H30Cl2O6
CAS Number
83919-23-7
Unique Ingredient Identifier
04201GDN4R
Background

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its ...

Indication

Inhaled mometasone furoate is indicated for prophylaxis of asthma in patients ≥4 years. Applied topically as an ointment, mometasone furoate is indicated for symptomatic treatment of dermatitis and pruritis in patients ≥2 years.
...

Associated Conditions
Asthma, Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), Dermatitis, Dermatitis, Eczematous caused by superficial Fungal skin infection, Moderate to Severe Plaque Psoriasis, Pruritus, Psoriasis, Psoriasis, Moderate to Severe, Seasonal Allergic Rhinitis, Seasonal Allergies, Skin Diseases, Eczematous, Skin Infections, Moderate, severe Seasonal Allergic Rhinitis, Ocular effects
Associated Therapies
-
Clinical Trials
Related News

A Comparative Study of Mometasone Furoate Nasal Spray and Fluticasone Propionate Nasal Spray in Patients With Perennial Allergic Rhinitis (Study P04512)

First Posted Date
2008-10-31
Last Posted Date
2022-02-09
Lead Sponsor
Organon and Co
Target Recruit Count
351
Registration Number
NCT00783224

Onset of Effect of Mometasone Nasal Spray in Induced Allergic Rhinitis (Study P03431)

Phase 4
Completed
Conditions
Allergic Rhinitis
Interventions
Drug: Placebo
Drug: Mometasone
First Posted Date
2008-10-31
Last Posted Date
2024-08-15
Lead Sponsor
Organon and Co
Target Recruit Count
340
Registration Number
NCT00783237

Equivalency Study of Two Formulations of Mometasone Furoate Nasal Spray (Study P04419)

Phase 3
Completed
Conditions
Rhinitis, Allergic, Perennial
Interventions
Drug: mometasone furoate
First Posted Date
2008-10-24
Last Posted Date
2024-08-15
Lead Sponsor
Organon and Co
Target Recruit Count
102
Registration Number
NCT00779740

A Study of Mometasone Furoate Nasal Spray in Perennial Allergic Rhinitis (Study P03748)(COMPLETED)

First Posted Date
2008-10-24
Last Posted Date
2024-08-15
Lead Sponsor
Organon and Co
Target Recruit Count
455
Registration Number
NCT00779545

Elocon vs Fluticasone in Localized Psoriasis (P03197)

Phase 4
Completed
Conditions
Psoriasis
Interventions
Drug: Mometasone
Drug: Fluticasone
First Posted Date
2008-10-01
Last Posted Date
2024-08-15
Lead Sponsor
Organon and Co
Target Recruit Count
245
Registration Number
NCT00763529

A Long-term Study of Mometasone Furoate in Patients With Perennial Allergic Rhinitis (Study P04459)

Phase 3
Completed
Conditions
Perennial Allergic Rhinitis
Interventions
Drug: Mometasone furoate
First Posted Date
2008-08-12
Last Posted Date
2024-08-15
Lead Sponsor
Organon and Co
Target Recruit Count
98
Registration Number
NCT00732368

A Phase I Study to Assess the Safety and Tolerability of Topical CRx-197 Formulations in Healthy Volunteers

First Posted Date
2008-07-24
Last Posted Date
2008-09-26
Lead Sponsor
Zalicus
Target Recruit Count
20
Registration Number
NCT00721331
Locations
🇩🇪

PROINNOVERA GmbH, Muenster, Germany

A Study to Evaluate the Safety and Tolerability of a Nasal Spray to Treat Perennial Allergic Rhinitis

First Posted Date
2008-07-22
Last Posted Date
2015-05-21
Lead Sponsor
Meda Pharmaceuticals
Target Recruit Count
703
Registration Number
NCT00720382
Locations
🇺🇸

Allergy and Asthma DTC, Tallahassee, Florida, United States

🇺🇸

Allergy and Consultants of NJ/PA, Collegeville, Pennsylvania, United States

🇺🇸

Pharmaceutical Research & Consulting Inc, Dallas, Texas, United States

and more 55 locations

Mometasone and Markers of Airway Inflammation

Phase 4
Completed
Conditions
Asthma
Interventions
Drug: Placebo
Drug: Mometasone Furoate
First Posted Date
2008-07-08
Last Posted Date
2008-07-08
Lead Sponsor
Creighton University
Target Recruit Count
12
Registration Number
NCT00711165
Locations
🇺🇸

Creighton University Medical Center, Omaha, Nebraska, United States

Clinical Trial to Assess Efficacy, Safety, Treatment Adherence and Quality of Life Impact of Mometasone Furoate in Asthmatic Patients (Study P04879)(TERMINATED)

Phase 4
Terminated
Conditions
Asthma
Interventions
Drug: Mometasone Furoate
First Posted Date
2008-05-30
Last Posted Date
2024-05-24
Lead Sponsor
Organon and Co
Target Recruit Count
385
Registration Number
NCT00687531
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