Mometasone
- Generic Name
- Mometasone
- Brand Names
- Asmanex, Dulera, Elocom, Elocon, Nasonex, Ryaltris, Sinuva, Zenhale, Atectura Breezhaler, Bemrist Breezhaler
- Drug Type
- Small Molecule
- Chemical Formula
- C27H30Cl2O6
- CAS Number
- 83919-23-7
- Unique Ingredient Identifier
- 04201GDN4R
Overview
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications.
Background
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications.
Indication
Inhaled mometasone furoate is indicated for prophylaxis of asthma in patients ≥4 years. Applied topically as an ointment, mometasone furoate is indicated for symptomatic treatment of dermatitis and pruritis in patients ≥2 years. Mometasone furoate nasal spray is available both over-the-counter (OTC) and by prescription. The OTC nasal spray formulation of mometasone furoate is indicated for the treatment of upper respiratory allergic symptoms (e.g. rhinorrhea, sneezing) in patients ≥2 years of age. The prescription formulation is indicated for the treatment of chronic rhinosinusitis with nasal polyps in patients ≥18 year old and for the and prophylaxis of seasonal allergic rhinitis in patients ≥12 years old. It is also approved in combination with olopatadine for the symptomatic treatment of seasonal allergic rhinitis in patients ≥12 years.
Associated Conditions
- Asthma
- Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)
- Dermatitis
- Dermatitis, Eczematous caused by superficial Fungal skin infection
- Moderate to Severe Plaque Psoriasis
- Pruritus
- Psoriasis
- Psoriasis, Moderate to Severe
- Seasonal Allergic Rhinitis
- Seasonal Allergies
- Skin Diseases, Eczematous
- Skin Infections
- Moderate, severe Seasonal Allergic Rhinitis
- Ocular effects
Clinical Trials
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Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2018/03/01 | Not Applicable | UNKNOWN | Shanghai Stomotological Hospital | ||
2017/10/27 | Phase 3 | Terminated | |||
2017/03/21 | Phase 3 | Completed | |||
2017/01/05 | Phase 4 | Completed | |||
2016/11/25 | Phase 1 | Completed | |||
2016/11/02 | Phase 3 | Withdrawn | EMS | ||
2016/11/02 | Phase 3 | Withdrawn | EMS | ||
2016/09/23 | Phase 3 | Completed | |||
2016/09/13 | Phase 3 | Completed | |||
2015/12/16 | Phase 3 | Completed | Glenmark Specialty S.A. |
FDA Approved Products
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Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
|---|---|---|---|---|---|
TOPICAL | 1 mg in 1 g | 2020/02/01 | 71205-413 | ||
TOPICAL | 1 mg in 1 g | 2022/06/14 | 50090-2991 | ||
RESPIRATORY (INHALATION) | 200 ug in 1 1 | 2021/06/01 | 78206-113 | ||
NASAL | 50 ug in 1 1 | 2011/04/27 | 54868-4174 | ||
TOPICAL | 1 mg in 1 g | 2021/02/11 | 68071-1538 | ||
TOPICAL | 1 mg in 1 g | 2010/08/31 | 54868-2223 | ||
TOPICAL | 1 mg in 1 g | 2017/10/23 | 45802-119 | ||
TOPICAL | 1 mg in 1 g | 2021/02/22 | 68071-4460 | ||
NASAL | 50 ug in 1 1 | 2024/03/22 | 59651-402 | ||
TOPICAL | 1 mg in 1 g | 2022/07/07 | 63629-9306 |
EMA Approved Products
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Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
|---|
No EMA products found
No EMA products found for this drug
HSA Approved Products
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Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
|---|
No HSA products found
No HSA products found for this drug
NMPA Approved Products
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Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|
No NMPA products found
No NMPA products found for this drug
PPB Approved Products
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
|---|---|---|---|---|---|
HK-56719 | vickmans laboratories ltd | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2008/06/20 | |
HK-63532 | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2015/03/09 | ||
HK-60645 | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2011/08/25 | ||
HK-62667 | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2014/03/11 | ||
HK-68048 | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2023/11/30 | ||
HK-68687 | bright future pharmaceuticals factory o/b bright future pharmaceutical laboratories limited | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2025/05/21 | |
HK-54865 | unicorn laboratories o/b american unicorn laboratories limited | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2006/10/13 | |
HK-60903 | Part 1, Schedule 1 & Schedule 3 Poison | POM | 2011/12/13 |
TGA Approved Products
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Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|---|---|---|---|---|
343458 | Active | 2020/09/14 | mometasone furoate monohydrate | ||
77112 | Active | 2001/02/14 | mometasone furoate | ||
58613 | Active | 1997/02/19 | mometasone furoate | ||
228266 | Active | 2014/09/22 | mometasone furoate monohydrate | ||
212416 | Active | 2013/09/11 | mometasone furoate | ||
206495 | Active | 2013/02/28 | mometasone furoate | ||
233571 | Active | 2016/01/06 | mometasone furoate monohydrate |