MedPath

Tegoprubart

Generic Name
Tegoprubart
Drug Type
Biotech
Unique Ingredient Identifier
EK87C62XNH

Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

Phase 1
Recruiting
Conditions
Diabetes Mellitus
First Posted Date
2024-03-12
Last Posted Date
2024-03-27
Lead Sponsor
University of Chicago
Target Recruit Count
3
Registration Number
NCT06305286
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients

Phase 2
Conditions
Kidney Transplant Rejection
Interventions
First Posted Date
2023-11-13
Last Posted Date
2025-05-02
Lead Sponsor
Eledon Pharmaceuticals
Target Recruit Count
132
Registration Number
NCT06126380
Locations
🇪🇸

Hospital Universitari de Bellvitge, Barcelona, Spain

🇫🇷

Groupe Hospitalier Pellegrin, Bordeaux, France

🇫🇷

CHU Grenoble-Alpes - Hopital Nord Michallon, Grenoble, France

and more 22 locations

Safety and Efficacy of Tegoprubart in Patients Undergoing Kidney Transplantation

Phase 2
Active, not recruiting
Conditions
Kidney Transplant Rejection
Interventions
First Posted Date
2023-08-09
Last Posted Date
2025-01-29
Lead Sponsor
Eledon Pharmaceuticals
Target Recruit Count
120
Registration Number
NCT05983770
Locations
🇺🇸

Tulane Medical Center, New Orleans, Louisiana, United States

🇺🇸

University of Maryland Medical Center, Baltimore, Maryland, United States

🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

and more 53 locations

Safety and Efficacy of AT-1501 in Patients With IgA Nephropathy (IgAN)

Phase 2
Terminated
Conditions
IgA Nephropathy
IgAN
Interventions
First Posted Date
2021-11-18
Last Posted Date
2024-03-26
Lead Sponsor
Eledon Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT05125068
Locations
🇹🇭

Chulalongkorn University, Pathum Wan, Bangkok, Thailand

🇹🇭

Prince of Songkla University, Dusit, Bangkok, Thailand

🇦🇺

Monash Medical Centre, Clayton, Victoria, Australia

and more 23 locations

Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant

Phase 1
Recruiting
Conditions
Kidney Transplant
Interventions
First Posted Date
2021-08-30
Last Posted Date
2025-05-04
Lead Sponsor
Eledon Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT05027906
Locations
🇧🇷

Fundação Oswaldo Ramos - Hospital do Rim, São Paulo, Brazil

🇺🇸

University of Cincinnati, Cincinnati, Ohio, United States

🇦🇺

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

and more 6 locations

Safety, Tolerability and Efficacy of Immunomodulation With AT-1501 in Islet Cell Transplantation

Phase 2
Withdrawn
Conditions
Type 1 Diabetes Mellitus
Interventions
First Posted Date
2021-01-15
Last Posted Date
2022-08-10
Lead Sponsor
Anelixis Therapeutics, LLC
Registration Number
NCT04711226
Locations
🇨🇦

University of Alberta, Edmonton, Alberta, Canada

Multiple Doses of AT-1501-A201 in Adults With ALS

Phase 2
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2020-03-26
Last Posted Date
2023-06-28
Lead Sponsor
Anelixis Therapeutics, LLC
Target Recruit Count
54
Registration Number
NCT04322149
Locations
🇺🇸

Augusta University, Augusta, Georgia, United States

🇺🇸

Texas Neurology, P.A., Dallas, Texas, United States

🇺🇸

Barrows Neurological Institute, Phoenix, Arizona, United States

and more 10 locations
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