Dopamine

Generic Name: Dopamine

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₈H_₁₁NO_₂

CAS Number: 51-61-6

Unique Ingredient Identifier: VTD58H1Z2X

Background: One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Indication: For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Associated Conditions: Arrhythmia, Circulatory collapse and shock, Hypotension caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Urine flow decreased caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Decreased cardiac output caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction

Associated Therapies: -

Clinical Trials

AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment

Phase 1

Recruiting

Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Renal Impairment

Interventions: Biological: AZD3427
Other: AZD3427 Placebo
Other: Radiolabelled ligand
Drug: Dopamine
Other: Saline

First Posted Date: 2024-09-25

Last Posted Date: 2024-12-05

Lead Sponsor: AstraZeneca

Target Recruit Count: 12

Registration Number: NCT06611423

Locations: 🇸🇪
Research Site, Solna, Sweden

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis

Not Applicable

Recruiting

Conditions: Secondary Hypertension Renal Arterial
Renal Artery Stenosis Atherosclerotic

Interventions: Drug: Dopamine
Diagnostic Test: Fractional Flow Reserve, Renal
Device: Renal artery stenting

First Posted Date: 2024-06-07

Last Posted Date: 2024-08-16

Lead Sponsor: Peking University First Hospital

Target Recruit Count: 200

Registration Number: NCT06447740

Locations: 🇨🇳
Peking University First Hospital, Beijing, Beijing, China

Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting

Not Applicable

Recruiting

Conditions: Renal Artery Stenosis Atherosclerotic
Secondary Hypertension Renal Arterial

Interventions: Drug: Dopamine
Diagnostic Test: Fractional Flow Reserve, Renal
Device: Renal artery stenting

First Posted Date: 2023-02-16

Last Posted Date: 2024-06-06

Lead Sponsor: Peking University First Hospital

Target Recruit Count: 100

Registration Number: NCT05732077

Locations: 🇨🇳
Peking University First Hospital, Beijing, Beijing, China
🇨🇳
Beijing Anzhen Hospital, Capital Medical University, Beijing, Beijing, China
🇨🇳
The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

and more 10 locations

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

Recruiting

Conditions: Late-Onset Neonatal Sepsis
Neonatal Hypotension
Extreme Prematurity

Interventions: Drug: Dopamine
Drug: Norepinephrine

First Posted Date: 2022-04-26

Last Posted Date: 2024-11-08

Lead Sponsor: Mount Sinai Hospital, Canada

Target Recruit Count: 550

Registration Number: NCT05347238

Locations: 🇺🇸
Banner-University Medical Center Phoenix, Phoenix, Arizona, United States
🇺🇸
Dayton Children's Hospital, Dayton, Ohio, United States
🇺🇸
El Paso Children's Hospital, El Paso, Texas, United States

and more 23 locations