Clavulanic acid
- Generic Name
- Clavulanic acid
- Brand Names
- Clavulin, Augmentin
- Drug Type
- Small Molecule
- Chemical Formula
- C8H9NO5
- CAS Number
- 58001-44-8
- Unique Ingredient Identifier
- 23521W1S24
- Background
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus.When it is combined with amoxi...
- Indication
Clavulanic acid combined with other antibiotics is indicated to prevent the development of drug-resistant strains of bacteria and promotes their therapeutic antibacterial effects.
The following conditions, when they produced beta-lactamases, have been treated with a combination of amoxicillin and clavulanic acid or ticarcillin and clavulanic acid:
...
- Associated Conditions
- Infection Due to Escherichia Coli, Skin and skin structure infections, Acute Uncomplicated Pyelonephritis, Bronchitis, Haemophilus Influenzae, Lower Respiratory Infection, Otitis Media (OM), Moraxella catarrhalis, Upper Respiratory Tract Infection, Acute Cystitis, Cysto-Urethritis, Bone and Joint Infections, Sinusitis, Intraabdominal Infections, Tonsillitis, Proteus mirabilis, Lower Respiratory Tract Infection (LRTI), Neisseria Gonorrhoeae Infection, Susceptible Bacterial Infections, Pharyngitis, Bacterial infection due to streptococcus, group A, Urinary Tract Infection, Septicemia, Bacterial Infections, Bacterial Pneumonia, Streptococcus Pneumoniae, Gynecological Infection
- Associated Therapies
- -
Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
- Conditions
- Interventions
- First Posted Date
- 2012-10-29
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Lawson Health Research Institute
- Registration Number
- NCT01715610
- Locations
- 🇨🇦
London Health Sciences Center, St. Joseph's Hospital, London, Ontario, Canada
The Use of Prophylactic Antibiotics In the Management of Dog Bites
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2006-12-05
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 125
- Registration Number
- NCT00185939
- Locations
- 🇺🇸
Stanford University Medical Center, Stanford, California, United States
🇺🇸Mills Peninsula Hospital, Burlingame, California, United States
🇺🇸UCSF Medical Center, San Francisco, California, United States
Acupuncture and Herbal Treatment of Chronic HIV Sinusitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Immune Enhancement Project
- Target Recruit Count
- 40
- Registration Number
- NCT00002149
- Locations
- 🇺🇸
Immune Enhancement Project, San Francisco, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.