Loperamide

Generic Name
Loperamide
Brand Names
Diamode, Imodium, Imodium Multi-symptom Relief
Drug Type
Small Molecule
Chemical Formula
C29H33ClN2O2
CAS Number
53179-11-6
Unique Ingredient Identifier
6X9OC3H4II
Background

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to pharmacologic...

Indication

Loperamide is indicated for the relief of diarrhea, including Travelers’ Diarrhea. As an off-label use, it is often used to manage chemotherapy-related diarrhea.

Associated Conditions
Diarrhea, Traveler's Diarrhea
Associated Therapies
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