Candesartan

Generic Name
Candesartan
Brand Names
Atacand, Atacand Hct
Drug Type
Small Molecule
Chemical Formula
C24H20N6O3
CAS Number
139481-59-7
Unique Ingredient Identifier
S8Q36MD2XX
Background

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.

Indication

May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Candesartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction an...

Associated Conditions
Hypertension, NYHA Functional Class II-IV Heart Failure
Associated Therapies
-

Study to Assess Potential Different Properties of Telmisartan Compared to Candesartan in Healthy Volunteers

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-10-10
Last Posted Date
2014-10-10
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
24
Registration Number
NCT02261116

Relative Bioavailability Study of Candesartan Cilexetil Under Fasting Conditions

First Posted Date
2014-10-01
Last Posted Date
2018-03-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
18
Registration Number
NCT02254447
Locations
🇮🇳

GSK Investigational Site, Hyderabad, India

Candesartan Cilexetil Special Drug Use Surveillance 「Challenge - Quality Control」

Completed
Conditions
Interventions
First Posted Date
2014-08-07
Last Posted Date
2018-11-05
Lead Sponsor
Takeda
Target Recruit Count
18113
Registration Number
NCT02211638

Blopress Tablets Specified Drug-use Survey "Hypertension: Survey on Patients With Metabolic Syndrome"

Completed
Conditions
Interventions
First Posted Date
2014-06-18
Last Posted Date
2016-09-28
Lead Sponsor
Takeda
Target Recruit Count
14151
Registration Number
NCT02166697

Pharmacokinetic Drug Interaction Between Candesartan and Rosuvastatin

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-03-05
Last Posted Date
2014-03-05
Lead Sponsor
Alvogen Korea
Target Recruit Count
40
Registration Number
NCT02079506
Locations
🇰🇷

Chungnam National University Hospital, Jung-gu, Daejeon, Korea, Republic of

Monotherapy-Controlled Study of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Combination in Subjects With Essential Hypertension Inadequately Controlled on Candesartan Cilexetil

First Posted Date
2014-01-28
Last Posted Date
2017-05-22
Lead Sponsor
Bayer
Registration Number
NCT02047019
Locations
🇮🇹

AAS 3 Friuli Alto Medio Collin, Udine, Friuli-Venezia Giulia, Italy

🇮🇹

IRCCS Ist Neurologico Mediterraneo, Isernia, Molise, Italy

🇮🇹

Fondazione Università G.D'Annunzio, Chieti, Abruzzo, Italy

and more 5 locations

CAndesartan vs LIsinopril Effects on the BRain

First Posted Date
2013-11-14
Last Posted Date
2021-02-21
Lead Sponsor
Emory University
Target Recruit Count
176
Registration Number
NCT01984164
Locations
🇺🇸

Emory Univeristy, Atlanta, Georgia, United States

Drug-Drug Interaction Study to Evaluate the Effect of Colestilan on the Pharmacokinetics of Single Doses of Candesartan Cilexetil in Healthy Subjects

First Posted Date
2013-11-06
Last Posted Date
2017-05-12
Lead Sponsor
Mitsubishi Tanabe Pharma Corporation
Target Recruit Count
18
Registration Number
NCT01976572
Locations
🇬🇧

Covance Clinical Research Unit Ltd., Leeds, Springfield House Hyde Street, United Kingdom

RAS Quantification in Patients With Aliskiren or Candesartan

First Posted Date
2013-04-09
Last Posted Date
2016-03-16
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT01827202
Locations
🇦🇹

Medical University of Vienna, Department of Internal Medicine III, Division of Nephrology and Dialysis, Vienna, Austria

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