Insulin degludec

Generic Name
Insulin degludec
Brand Names
Ryzodeg, Tresiba, Xultophy
Drug Type
Biotech
Chemical Formula
-
CAS Number
844439-96-9
Unique Ingredient Identifier
54Q18076QB
Background

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose metabolism. ...

Indication

Insulin degludec is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus.

Associated Conditions
Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Associated Therapies
-

A Research Study of a New Medicine NNC0363-1063 in Healthy Participants and Participants With Type 1 Diabetes

First Posted Date
2024-11-12
Last Posted Date
2024-11-19
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
154
Registration Number
NCT06685185
Locations
🇩🇪

Profil Institut für Stoffwechselforschung GmbH, Neuss, Germany

A Clinical Study of GZR33 and GZR101 in Healthy Subjects

First Posted Date
2024-08-16
Last Posted Date
2024-08-16
Lead Sponsor
Gan and Lee Pharmaceuticals, USA
Target Recruit Count
28
Registration Number
NCT06556641
Locations
🇨🇳

Study Site, Xingtai, Hebei, China

A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GZR4 in Subjects With Type 2 Diabetes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-08-14
Last Posted Date
2024-08-14
Lead Sponsor
Gan and Lee Pharmaceuticals, USA
Target Recruit Count
36
Registration Number
NCT06553248
Locations
🇨🇳

Gan & Lee Pharmaceuticals Co., Ltd, Beijing, Beijing, China

A Study to Test How a New Long-acting Insulin Works in the Body of Patients With Type 2 Diabetes During Exercise and Prolonged Fasting

First Posted Date
2024-03-01
Last Posted Date
2024-04-02
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
30
Registration Number
NCT06288412
Locations
🇦🇹

Medical University of Graz, Graz, Austria

A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)

First Posted Date
2024-02-28
Last Posted Date
2024-05-31
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
70
Registration Number
NCT06280703
Locations
🇩🇪

Profil Institut für Stoffwechselforschung, Neuss, Nordrhein-Westfalen, Germany

A Trial Comparing the Efficacy and Safety of GZR4 Injection Versus Insulin Degludec in Subjects with Type 2 Diabetes Mellitus

First Posted Date
2024-01-11
Last Posted Date
2024-12-09
Lead Sponsor
Gan and Lee Pharmaceuticals, USA
Target Recruit Count
179
Registration Number
NCT06202079
Locations
🇨🇳

Study Site 01, Tianjin, China

🇨🇳

Study Site 02, Beijing, China

🇨🇳

Study Site 05, Beijing, China

and more 5 locations

Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness Hyperglycemia

First Posted Date
2023-12-21
Last Posted Date
2024-08-05
Lead Sponsor
Ain Shams University
Target Recruit Count
90
Registration Number
NCT06178874
Locations
🇪🇬

Ain shams university, Cairo, Egypt

A Research Study in Saudi Arabia to Understand How the Dose Check App Used With Tresiba Treatment Helps to Control Blood Sugar Level

First Posted Date
2023-12-01
Last Posted Date
2024-07-05
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
175
Registration Number
NCT06153537
Locations
🇸🇦

My clinic, Jeddah, Saudi Arabia

🇸🇦

Al Hammadi, Riyadh, Saudi Arabia

🇸🇦

Almoosa Specialist Hospital, Ihsaa, Saudi Arabia

and more 8 locations

A Study to Investigate the Safety and Tolerability of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes Mellitus

First Posted Date
2023-11-15
Last Posted Date
2024-07-24
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
66
Registration Number
NCT06132126
Locations
🇺🇸

Labcorp CRU, Dallas, Texas, United States

🇺🇸

Qps-Mra, Llc, Miami, Florida, United States

🇺🇸

CenExel ACT, Anaheim, California, United States

A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy

First Posted Date
2022-07-19
Last Posted Date
2024-07-29
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
692
Registration Number
NCT05463744
Locations
🇺🇸

Palm Research Center Tenaya, Las Vegas, Nevada, United States

🇺🇸

Biopharma Informatic, LLC, Houston, Texas, United States

🇺🇸

Amir A Hassan, MD, PA, Houston, Texas, United States

and more 79 locations
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